{"id":1135,"date":"2025-06-24T14:02:48","date_gmt":"2025-06-24T06:02:48","guid":{"rendered":"https:\/\/imi.nycu.edu.tw\/%e8%94%a1%e6%98%8e%e7%bf%b0%e5%89%af%e6%95%99%e6%8e%88\/"},"modified":"2026-03-25T13:47:50","modified_gmt":"2026-03-25T05:47:50","slug":"ming-han-tsai","status":"publish","type":"post","link":"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/","title":{"rendered":"Ming-Han Tsai"},"content":{"rendered":"<div class=\"row\"  id=\"row-1200280954\">\n\n\t<div id=\"col-994541870\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<ul>\n<li>\n<p>Associate Professor<br \/>Institute of Microbiology and Immunology<\/p>\n<\/li>\n<li>\n<p>Research Interests: Virology; Biotechnology; Cancer Biology; Immunology; Drug Screening<\/p>\n<\/li>\n<li>\n<p>Office: Room R411, Biomedical Building<\/p>\n<\/li>\n<li>\n<p>Tel (Office): +886-2-2826-7109<\/p>\n<\/li>\n<li>\n<p>Tel (Laboratory): +886-2-2826-7000 ext. 65626<\/p>\n<\/li>\n<li>E-mail: m.tsai@nycu.edu.tw<\/li>\n<li>Website:\/\/wisewind1005.wixsite.com\/tsaimh-ebv<\/li>\n<li>ORCID:\u00a0<a href=\"https:\/\/orcid.org\/0000-0001-5563-3057\">0000-0001-5563-3057\u00a0<\/a><\/li>\n<\/ul>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1218016959\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<p><img\nfetchpriority=\"high\"\ndecoding=\"async\"\nwidth=\"795\"\nheight=\"1024\"\nsrc=\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai-795x1024.jpg\"\nclass=\"attachment-large size-large\"\nalt=\"Ming-Han Tsai \u8521\u660e\u7ff0\u526f\u6559\u6388\"\nsrcset=\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai-795x1024.jpg 795w,\nhttps:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai-233x300.jpg 233w,\nhttps:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai-768x989.jpg 768w,\nhttps:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai-1193x1536.jpg 1193w,\nhttps:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai.jpg 1200w\"\nsizes=\"(max-width: 795px) 100vw, 795px\"><\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n<\/div>\n\n\t\t<div class=\"tabbed-content\">\n\t\t\t\n\t\t\t<ul class=\"nav nav-tabs nav-uppercase nav-size-normal nav-left\" role=\"tablist\"><li id=\"tab-professional-experience\" class=\"tab active has-icon\" role=\"presentation\"><a href=\"#tab_professional-experience\" role=\"tab\" aria-selected=\"true\" aria-controls=\"tab_professional-experience\"><span>Professional Experience<\/span><\/a><\/li>\n<li id=\"tab-selected-honors-and-awards\" class=\"tab has-icon\" role=\"presentation\"><a href=\"#tab_selected-honors-and-awards\" tabindex=\"-1\" role=\"tab\" aria-selected=\"false\" aria-controls=\"tab_selected-honors-and-awards\"><span>Selected Honors and Awards<\/span><\/a><\/li>\n<li id=\"tab-publications-and-research-projects\" class=\"tab has-icon\" role=\"presentation\"><a href=\"#tab_publications-and-research-projects\" tabindex=\"-1\" role=\"tab\" aria-selected=\"false\" aria-controls=\"tab_publications-and-research-projects\"><span>Publications and Research Projects<\/span><\/a><\/li>\n<li id=\"tab-laboratory-overview\" class=\"tab has-icon\" role=\"presentation\"><a href=\"#tab_laboratory-overview\" tabindex=\"-1\" role=\"tab\" aria-selected=\"false\" aria-controls=\"tab_laboratory-overview\"><span>Laboratory Overview<\/span><\/a><\/li><\/ul><div class=\"tab-panels\"><div id=\"tab_professional-experience\" class=\"panel active entry-content\" role=\"tabpanel\" aria-labelledby=\"tab-professional-experience\">\n<table>\n<caption>Education \/ Professional Experience<\/caption>\n<thead>\n<tr>\n<th scope=\"col\">Institution<\/th>\n<th scope=\"col\">Degree \/ Position<\/th>\n<th scope=\"col\">Field of Research<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 (NYCU)<\/td>\n<td>Associate Professor (2023\u2013)<\/td>\n<td>Applied Virology, Biotechnology, Immunotherapy<\/td>\n<\/tr>\n<tr>\n<td>\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 (NYCU)<\/td>\n<td>Assistant Professor (2018\u20132023)<\/td>\n<td>Virology, Biotechnology, and Cancer Biology<\/td>\n<\/tr>\n<tr>\n<td>\u5fb7\u570b\u764c\u75c7\u7814\u7a76\u4e2d\u5fc3 (German Cancer Research Center, DKFZ, Germany)<\/td>\n<td>Scientist (2015\u20132017)<\/td>\n<td>Virology and Biotechnology<\/td>\n<\/tr>\n<tr>\n<td>\u5fb7\u570b\u6d77\u5fb7\u5821\u5927\u5b78 (Ruprecht Karl University of Heidelberg, Germany)<\/td>\n<td>Ph.D. (2015)<\/td>\n<td>Virology and Oncology<\/td>\n<\/tr>\n<tr>\n<td>\u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662 (NHRI, Taiwan)<\/td>\n<td>Research Assistant (2007\u20132010)<\/td>\n<td>Virology, Antiviral Drug Development<\/td>\n<\/tr>\n<tr>\n<td>\u570b\u7acb\u6e05\u83ef\u5927\u5b78<\/td>\n<td>M.S. (2006)<\/td>\n<td>Biotechnology and Immunology<\/td>\n<\/tr>\n<tr>\n<td>\u570b\u7acb\u6e05\u83ef\u5927\u5b78<\/td>\n<td>B.S. (2004)<\/td>\n<td>Life Science<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<div id=\"tab_selected-honors-and-awards\" class=\"panel entry-content\" role=\"tabpanel\" aria-labelledby=\"tab-selected-honors-and-awards\">\n<ol>\n<li>\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78\u512a\u826f\u6559\u5b78\u734e,Sep 2025.<\/li>\n<li>\u570b\u79d1\u6703\u5433\u5927\u7337\u5148\u751f\u7d00\u5ff5\u734e, 2023<\/li>\n<li>MOST Young Scholar Fellowship, Taiwan\u00a0(\u79d1\u6280\u90e8\u5e74\u8f15\u5b78\u8005\u990a\u6210\u8a08\u756b), 2018-2023<\/li>\n<li>\u7f8e\u570b\u3001\u97d3\u570b\u3001\u4fc4\u7f85\u65af\u7b49\u570b\u969b\u767c\u660e\u734e\u91d1\u724c, 2022, 2023<\/li>\n<li>\u8ca1\u5718\u6cd5\u4eba\u6c88\u529b\u63da\u6559\u6388\u91ab\u5b78\u6559\u80b2\u734e\u5b78\u7d00\u5ff5\u57fa\u91d1\u6703\/\u8b1b\u5e2b\u53ca\u7814\u7a76\u8207\u9032\u4fee\u734e\u52a9\u91d1, 2020,2021<\/li>\n<li>\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78110\u00a0\u5e74\u5ea6\u512a\u826f\u5c0e\u5e2b, Sep 2021<\/li>\n<li>\u570b\u7acb\u967d\u660e\u5927\u5b78109 \u5e74\u5ea6\u826f\u5e2b\u76ca\u53cb\u5c0e\u5e2b, Sep 2020<br \/><strong style=\"color: #555555;\">\u5176\u4ed6\u8cc7\u8a0a https:\/\/wisewind1005.wixsite.com\/tsaimh-ebv\/pi<\/strong><\/li>\n<\/ol>\n<\/div>\n<div id=\"tab_publications-and-research-projects\" class=\"panel entry-content\" role=\"tabpanel\" aria-labelledby=\"tab-publications-and-research-projects\">\n<h2><strong>Publications<\/strong><\/h2>\n<p>Website: https:\/\/wisewind1005.wixsite.com\/tsaimh-ebv\/publications<\/p>\n<p>ORCID: <a href=\"https:\/\/orcid.org\/0000-0001-5563-3057\">https:\/\/orcid.org\/0000-0001-5563-3057<\/a><\/p>\n<p>\u00a0<\/p>\n<p>A1. 2018-now (annotated by JCR 2025 https:\/\/jcr.clarivate.com\/jcr\/home)<\/p>\n<ol>\n<li>Ren-Jie Weng#, Li-Syuan Wu#, Darwin Kurniawan, Ching-Tzu Chang, Ming-Han Tsai*, Wei-Hung Chiang*(2025, Oct).\u00a0<u>Plasma-Guided Green Synthesis of Crystalline Graphene Quantum Dots for Broad-Spectrum Antiviral Applications.<\/u>\u00a0Chemical Engineering Journal (<u>3%<\/u>: 3\/83 ENGINEERING, ENVIRONMENTAL, IF 13.2)\u00a0(Accepted, *corresponding).<\/li>\n<li>Di Ngoc Kha Vo, Ha Phan Thanh Ho, Li-Syuan Wu, Yi-Yun Chen, Hang Thi Viet Trinh, Tung-Yi Lin, Yat-Yuen Lim, Keng-Chang Tsai, Ming-Han Tsai*(2025, Mar).\u00a0<u>Broad-spectrum antiviral activity of Ganoderma microsporum immunomodulatory protein: Targeting glycoprotein gB to inhibit EBV and HSV-1 infections via viral fusion blockage.<\/u>\u00a0International Journal of Biological Macromolecules, (<u>5.9%<\/u>: 6\/94 Polymer Science, IF 8.2)\u00a0Volume 307, Part 3, May 2025, 142179 (*corresponding).<\/li>\n<li>Yi Chiung Hsu, Ming-Han Tsai, Guani Wu, Chien Liang Liu, Yuan Ching Chang, Hung Bun Lam, Pei Yu Su, Chun Fan Lung, Po Sheng Yang.(2024, Mar). Role of\u00a0<u>Epstein-Barr Virus in Breast Cancer: Correlation with Clinical Outcome and Survival Analysis.<\/u>\u00a0Journal of Cancer, 2024 Mar 4;15(8):2403\u20132411.<\/li>\n<li>Wing Chung Tang, Sai Wah Tsao, Gareth E Jones, Xiong Liu, Ming-Han Tsai, Henri-Jacques Delecluse , Wei Dai, Chanping You, Jun Zhang, Shaina Chor Mei Huang, Manton Man-Hon Leung, Tengfei Liu, Yick Pang Ching, Honglin Chen, Kwok Wai Lo, Xin Li, Chi Man Tsang\u00a0(2023, Feb).\u00a0<u>Latent membrane protein 1 and macrophage-derived TNF\u03b1 synergistically activate and mobilize invadopodia to drive invasion of nasopharyngeal carcinoma<\/u>.\u00a0Journal of Pathology (<u>7.2%<\/u>, 7\/90 PATHOLOGY),\u00a010.1002\/path.6036<\/li>\n<li>Di Ngoc Kha Vo, Ha Phan Thanh Ho, Tung-Yi Lin, Jo-Ning Hung, Ya-Hui Chiu, Ming-Han Tsai*(2022, Sep).Ganoderma microsporum immunomodulatory protein acts as a multifunctional broadspectrum antiviral against SARS-CoV-2 by interfering virus binding to the host cells and spike-mediated cell fusion.\u00a0BIOMEDICINE &amp; PHARMACOTHERAPY (<u>5.3%<\/u>, 19\/3522 PHARMACOLOGY &amp; PHARMACY),\u00a0Vol 155, 113766. doi.org\/10.1016\/j.biopha.2022.113766. (*corresponding)<\/li>\n<li>Jo-Ning Hung, Di Ngoc Kha Vo, Ha Phan Thanh Ho, Ming-Han Tsai*\u00a0(2022, Aug).\u00a0PEDOT:PSS in solution form exhibits a strong potential in inhibiting SARS-CoV-2 infection of the host cells by targeting viruses and also the host cells.\u00a0BIOMACROMOLECULES (ACS publications)(<u>4.4%<\/u>, 3\/57\u00a0CHEMISTRY, ORGANIC)\u00a023(9),3535-3548. doi.org\/10.1021\/acs.biomac.2c00271.\u00a0(*corresponding)<\/li>\n<li>Hsin Yeh, Di Ngoc Kha Vo, Zhi-Hu Lin, Ha Phan Thanh Ho, Wei-Jyun Hua, Wei-Lun Qiu, Ming-Han Tsai*, Tung-Yi Lin* (2022, May).\u00a0GMI, a protein from Ganoderma microsporum, induces ACE2 degradation to alleviate infection of SARS-CoV-2 Spike-pseudotyped virus.\u00a0PHYTOMEDICINE(<u>1%<\/u>, 1\/45\u00a0INTEGRATIVE &amp; COMPLEMENTARY MEDICINE, IF 8.2),\u00a0103:154215. doi: 10.1016\/j.phymed.2022.154215.\u00a0(*corresponding)<\/li>\n<li>Jen-Mei Chou, Jo-Ling Tsai, Jo-Ning Hung, I-Hua Chen, Szu-Ting Chen, MingHan Tsai* (2022, May).\u00a0<a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmicb.2022.883597\/full#:~:text=Because%20ORF8%20is%20important%20for,the%20inhibitory%20effects%20of%20ORF8.\">The ORF8 Protein of SARS-CoV-2 Modulates the Spike Protein and Its Implications in Viral Transmission.<\/a>\u00a0Frontiers in Microbiology, 19;13:883597.\u00a0(*corresponding)<\/li>\n<li>Zhe Li, Francesco Baccianti, Susanne Delecluse, Ming-Han Tsai, Anatoliy Shumilov, Xianliang Cheng, Sicong Ma, Ingrid Hoffmann, Remy Poirey, Henri-Jacques Delecluse (2021, Oct).\u00a0The Epstein-Barr virus non-coding RNA EBER2 transactivates the UCHL1 deubiquitinase to accelerate cell growth.\u00a0PNAS (10%, 14\/135\u00a0MULTIDISCIPLINARY SCIENCES, IF 9.1), 118 (43) e2115508118<\/li>\n<li>Hsieh, H.Y., Chang, R., Huang, Y.Y., Juan, P.H., Tahara, H., Lee, K.Y., Vo, D.N.K., Tsai, M.H., Wei, P.K., Sheen, H.J., Fan, Y.J. \u00a0, 2021.\u00a0Continuous polymerase chain reaction microfluidics integrated with a gold-capped nanoslit sensing chip for Epstein-Barr virus detection.\u00a0Biosensors and Bioelectronics (<u>2.3%<\/u>, 3\/111\u00a0CHEMISTRY, ANALYTICAL, IF 10.5)\u00a010.1016\/j.bios.2021.113672<\/li>\n<li>Susanne Delecluse, Remy Poirey, Martin Zeier, Paul Schnitzler, Uta Behrends, Ming-Han Tsai*, Henri-Jacques Delecluse* \u00a02020. \u00a0Identification and cloning of a new Western Epstein-Barr Virus strain that efficiently replicates in primary B cells.\u00a0<u>J. Virol<\/u>. DOI: 10.1128\/JVI.01918-19.\u00a0(*corresponding)<\/li>\n<li><u>Zhe Li#, Ming-Han Tsai#<\/u>, Anatoliy Shumilov, Francesco Baccianti, Sai Wah Tsao, Remy Poirey, R, Henr-Jacques Delecluse,(2019, Sep).<a href=\"https:\/\/www.nature.com\/articles\/s41564-019-0546-y\">\u00a0A non-coding RNA from a carcinogenic virus induces an inflammatory response to promote virus production in infected cells.<\/a>\u00a0Nature Microbiology (2%, 4\/163 MICROBIOLOGY, IF 19.2). doi: 10.1038\/s41564-019-0546-y\u00a0<u>(#co-first author)<\/u><\/li>\n<li>Delecluse, S.,<u>\u00a0Tsai, M.H.<\/u>, Shumilov, A., Bencun, M., Arrow, S., Beshirova, A., Cottignies-Calamarte, A., Lasitschka, F., Bulut, OC., M\u00fcnz, C., Zeier, M., Behrends, U., Delecluse, H.J.. 2019.\u00a0Epstein-Barr virus induces expression of the LPAM-1 integrin in B cells in vitro and in vivo.\u00a0<u>J. Virol<\/u>. 19;93(5). pii: e01618-18.<\/li>\n<li>Tian, J.N., Yang, C.C., Chuang, C.K.,<u>\u00a0Tsai, M.H.<\/u>, Wu, R.H., Chen, C.T., Yueh. A. 2019.\u00a0<a href=\"https:\/\/www.mdpi.com\/1999-4915\/11\/9\/787\">A Dengue virus type 2 (DENV-2) NS4B-Interacting host factor, SERP1, reduces DENV-2 production by suppressing viral RNA replication.<\/a>\u00a0<u>Viruses<\/u>\u00a011(9):787. doi: 10.3390\/v11090787.<\/li>\n<li>van Zyl, D.G.,<u>Tsai, M.H.<\/u>,\u00a0Shumilov, A., Schneidt, V., Poirey, R., Schlehe, B., Fluhr, H., Mautner, J., Delecluse, H.J.. 2018.\u00a0<a href=\"https:\/\/journals.plos.org\/plospathogens\/article?id=10.1371\/journal.ppat.1007464\">Immunogenic particles with a broad antigenic spectrum stimulate cytolytic T cells and offer increased protection against EBV infection ex vivo and in mice.<\/a>\u00a0PLoS Pathogens\u00a014(12):e1007464<\/li>\n<li>Bencun, M., Klinke, O., Hotz-Wagenblatt, A., Klaus, S.,\u00a0<u>Tsai, M.H.<\/u>, Poirey, R., Delecluse, H.J. 2018.\u00a0Translational profiling of B cells infected with the Epstein-Barr virus reveals 5\u2019 leader ribosome recruitment through upstream opening reading frames.\u00a0Nucleic Acids Res.\u00a06;46(6):2802-2819.<\/li>\n<li>Gupta, S., Yl\u00e4-Anttila, P., Callegari, S.,\u00a0<u>Tsai, M.H.<\/u>, Delecluse, H.J., Masucci, M.G. 2018.\u00a0<a href=\"https:\/\/journals.plos.org\/plospathogens\/article?id=10.1371\/journal.ppat.1006852\">Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome.<\/a>\u00a0PLoS Pathogens\u00a014(1):e1006852.<\/li>\n<\/ol>\n<p>A2. Up to 2017\u200b<\/p>\n<ol>\n<li><u>Shumilov, A.*, Tsai, M.H.*, (*co-first author, listed by last name alphabetically)<\/u>, Schlosser, Y., Kratz, A.S., Bernhardt, K., Fink, S., Mizani, T., Lin, X., Jauch, A., Mautner, J., et al. 2017.\u00a0<a href=\"https:\/\/www.nature.com\/articles\/ncomms14257\">Epstein-Barr virus particles induce centrosome amplification and chromosomal instability<\/a>.\u00a0<u>Nature Communications<\/u>.\u00a0doi:10.1038\/ncomms14257.<\/li>\n<li>Wu, R.H.,\u00a0<u>Tsai, M.H.<\/u>, Tsai, K.N., Tian, J.N., Wu, J.S., Wu, S.Y., Chern, J.H., Chen, C.H., and Yueh, A. 2017.\u00a0Mutagenesis of Dengue Virus Protein NS2A Revealed a Novel Domain Responsible for Virus-Induced Cytopathic Effect and Interactions Between NS2A and NS2B Transmembrane Segments.\u00a0<u>J. Virol<\/u>\u00a0doi: 10.1128\/jvi.01836-16<\/li>\n<li><u>Ma, S.D.*, Tsai, M.H.* (*co-first author, listed by last name alphabetically)<\/u>, Romero-Masters, J., Ranheim, E.A., Bristol, J.A., Delecluse, H.J., and Kenney, S.C. 2017.\u00a0Epstein-Barr virus (EBV) can induce B cell lymphomas in a cord blood-humanized mouse model in the absence of LMP2A and LMP1 expression.\u00a0<u>J. Virol.<\/u>\u00a0doi: 10.1128\/jvi.01928-16.<\/li>\n<li>Bilger, A., Plowshay, J., Ma, S.D., Nawandar, D., Barlow, E.A., Romero-Masters, J.C., Bristol, J.A., Li, Z.,\u00a0\u00a0<u>Tsai, M.H.<\/u>, Delecluse, H.J., Kenny, S.C. 2017. L<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5546479\/\">eflunomide\/teriflunomide inhibit EBV-induced lymphoproliferative disease and lytic replication.<\/a>\u00a0<u>Oncotarget.<\/u>\u00a08: 44266-33280<\/li>\n<li>Fink, S.,\u00a0<u>Tsai, M.H.<\/u>, Schnitzler, P., Zeier, M., Dreger, P., Wuchter, P., Bulut, O.C., Behrends, U., and Delecluse, H.J. 2017.\u00a0The Epstein-Barr virus DNA load in the peripheral blood of transplant recipients does not accurately reflect the burden of infected cells.\u00a0<u>Transpl Int<\/u>\u00a030:57-67.<\/li>\n<li><u>Tsai, M.H.<\/u>, Lin, X., Shumilov, A., Bernhardt, K., Feederle, R., Poirey, R., Kopp-Schneider, A., Pereira, B., Almeida, R., and Delecluse, H.J. 2016.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5354655\/\">The biological properties of different Epstein-Barr virus strains explain their association with various types of cancers.<\/a>\u00a0<u>Oncotarget.\u00a0<\/u>10.18632\/oncotarget.14380<\/li>\n<li>Bernhardt, K., Haar, J.,\u00a0<u>Tsai, M.H.<\/u>, Poirey, R., Feederle, R., and Delecluse, H.J. 2016.\u00a0<a href=\"https:\/\/journals.plos.org\/plospathogens\/article?id=10.1371\/journal.ppat.1005405\">A Viral microRNA Cluster Regulates the Expression of PTEN, p27 and of a bcl-2 Homolog<\/a>.\u00a0<u>PLoS Pathogens<\/u>\u00a012:e1005405.<\/li>\n<li>Wu, R.H.,\u00a0<u>Tsai, M.H.<\/u>, Chao, D.Y., and Yueh, A. 2015.\u00a0Scanning mutagenesis studies reveal a potential intramolecular interaction within the C-terminal half of dengue virus NS2A involved in viral RNA replication and virus assembly and secretion.\u00a0<u>J. Virol.<\/u>\u00a089:4281-4295.<\/li>\n<li><u>Lin, XC*, Tsai, M.H.* (*co-first author, listed by last name alphabetically)<\/u>, Shumilov, A., Poirey, R., Bannert, H., Middeldorp, J.M., Feederle, R., and Delecluse, H.J. 2015. The Epstein-Barr Virus BART miRNA Cluster of the M81 Strain Modulates Multiple Functions in Primary B Cells.\u00a0<u>PLoS Pathogens\u00a0<\/u>11:e1005344.<\/li>\n<li>Hou, M.S., Huang, S.T.,\u00a0<u>Tsai, M.H.<\/u>, Yen, C.C., Lai, Y.G., Liou, Y.H., Lin, C.K., and Liao, N.S. 2015.\u00a0The interleukin-15 system suppresses T cell-mediated autoimmunity by regulating negative selection and nT(H)17 cell homeostasis in the thymus.<u>\u00a0J Autoimmun<\/u>\u00a056:118-129.<\/li>\n<li>Feederle, R., Klinke, O., Kutikhin, A., Poirey, R.,\u00a0<u>Tsai, M.H.<\/u>, and Delecluse, H.J. 2015.\u00a0<a href=\"https:\/\/link.springer.com\/chapter\/10.1007\/978-3-319-22822-8_7\">Epstein-Barr Virus: From the Detection of Sequence Polymorphisms to the Recognition of Viral Types.<\/a>\u00a0<u>Curr Top Microbiol Immunol<\/u>\u00a0390:119-148.<\/li>\n<li>Pu, S.Y., Wu, R.H.,\u00a0<u>Tsai, M.H.<\/u>, Yang, C.C., Chang, C.M., and Yueh, A. 2014.\u00a0<a href=\"https:\/\/www.microbiologyresearch.org\/content\/journal\/jgv\/10.1099\/vir.0.064915-0\">A novel approach to propagate flavivirus infectious cDNA clones in bacteria by introducing tandem repeat sequences upstream of virus genome.<\/a>\u00a0<u>J Gen Virol<\/u>\u00a095:1493-1503.<\/li>\n<li>Antsiferova, O., Muller, A., Ramer, P.C., Chijioke, O., Chatterjee, B., Raykova, A., Planas, R., Sospedra, M., Shumilov, A.,\u00a0<u>Tsai, M.H.<\/u>, et al. 2014.\u00a0<a href=\"https:\/\/journals.plos.org\/plospathogens\/article?id=10.1371\/journal.ppat.1004333\">Adoptive transfer of EBV specific CD8+ T cell clones can transiently control EBV infection in humanized mice<\/a>.\u00a0<u>PLoS Pathogens\u00a0<\/u>10:e1004333.<\/li>\n<li>Yang, C.C.,\u00a0<u>Tsai, M.H.<\/u>, Hu, H.S., Pu, S.Y., Wu, R.H., Wu, S.H., Lin, H.M., Song, J.S., Chao, Y.S., and Yueh, A. 2013.\u00a0Characterization of an efficient dengue virus replicon for development of assays of discovery of small molecules against dengue virus.\u00a0<u>Antiviral Res<\/u>\u00a098:228-241.<\/li>\n<li><u>Tsai, M.H.<\/u>, Raykova, A., Klinke, O., Bernhardt, K., Gartner, K., Leung, C.S., Geletneky, K., Sertel, S., Munz, C., Feederle, R., et al. 2013.\u00a0Spontaneous lytic replication and epitheliotropism define an Epstein-Barr virus strain found in carcinomas.\u00a0<u>Cell Rep<\/u>\u00a05:458-470. (Spotlight article in the review Frappier, L. 2013.\u00a0A cancer-associated Epstein-Barr virus variant with epithelial tropism.\u00a0<u>Trends Microbiol<\/u>\u00a021:616-617)<\/li>\n<li>Pu, S.Y., Wu, R.H., Yang, C.C., Jao, T.M.,\u00a0<u>Tsai, M.H.<\/u>, Wang, J.C., Lin, H.M., Chao, Y.S., and Yueh, A. 2011.\u00a0Successful propagation of flavivirus infectious cDNAs by a novel method to reduce the cryptic bacterial promoter activity of virus genomes.\u00a0<u>J. Virol.<\/u>\u00a085:2927-2941.<\/li>\n<li>Lai, Y.G., Hou, M.S., Hsu, Y.W., Chang, C.L., Liou, Y.H.,\u00a0<u>Tsai, M.H.<\/u>, Lee, F., and Liao, N.S. 2008.\u00a0IL-15 does not affect IEL development in the thymus but regulates homeostasis of putative precursors and mature CD8 alpha alpha+ IELs in the intestine.\u00a0<u>J Immunol<\/u>\u00a0180:3757-3765.<\/li>\n<\/ol>\n<h2><strong>Patents<\/strong><\/h2>\n<ol>\n<li>\u767c\u660e\u5c08\u5229: \u9810\u9632\u76b0\u75b9\u75c5\u6bd2\u611f\u67d3\u4eba\u985e\u7d30\u80de\u7684\u65b9\u6cd5<br \/>METHOD FOR PREVENTING HUMAN CELL INFECTION BY HERPESVIRUSES<br \/>\u7f8e\u570bUS 12,018,055 B2 \u8521\u660e\u7ff0,\u6797\u6771\u6bc5 \u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78<\/li>\n<\/ol>\n<ol start=\"2\">\n<li>\u767c\u660e\u5c08\u5229: \u4e00\u7a2e\u5305\u542b\u805a3,4-\u4e59\u70ef\u4e8c\u6c27\u567b\u5429-\u805a\u82ef\u4e59\u70ef\u78fa\u9178\u9e7d(PEDOT:PSS)\u4e4b\u6297\u75c5\u6bd2\u7d44\u5408\u7269\u7528\u65bc\u88fd\u5099\u9810\u9632\u6216\u6cbb\u7642\u51a0\u72c0\u75c5\u6bd2\u76f8\u95dc\u75be\u75c5\u4e4b\u91ab\u85e5\u7d44\u5408\u7269\u4ee5\u53ca\u5176\u7528\u65bc\u5728\u6d3b\u9ad4\u5916\u964d\u4f4e\u51a0\u72c0\u75c5\u6bd2\u611f\u67d3\u7387\u7684\u7528\u9014<br \/>\u4e2d\u83ef\u6c11\u570bI823333, \u8521\u660e\u7ff0, \u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78<\/li>\n<li>\u767c\u660e\u5c08\u5229:IMPROVED EBV VACCINEUS;<br \/>WO; JP; CNUS11097003B2 Henri-Jacques Delecluse, Anatoliy Shumilov, Ming-Han Tsai, Deutsches Krebsforschungszentrum (DKFZ), Germany<\/li>\n<li>\u767c\u660e\u5c08\u5229: IMMUNOMODUL ATORY PROTEIN FOR PREVENTION OF CORONAVIRUS INFECTIONUS;<br \/>TWUS2023233632A1, Tung-Yi Lin, Ming-Han\u00a0Tsai, National Yang Ming Chiao Tung University<\/li>\n<li>\u767c\u660e\u5c08\u5229: METHODS OF PREVENTING OR TREATING CORONAVIRUS INFECTION REDUCING CORONAVIRUS RATE IN VITRO WITH ANTIVIRAL COMPOSITION COMPRISING POLY(3,4 ETHYLENEDIOXYTHIOPHENE):POLY(STYRENE SULFONATE)<br \/>US; TW US20230321138A1<br \/>Ming-Han Tsai, National Yang Ming Chiao Tung University<strong style=\"color: #555555;\"><u>\u200b<\/u><\/strong><strong style=\"color: #555555;\"><u>\u200b<\/u><\/strong><\/li>\n<\/ol>\n<h2><strong> PRESENTATIONS<\/strong><\/h2>\n<ol>\n<li>EBV and human diseases. Invited speaker in 86th Japanese Society of Hematology, Kyoto, Japan, Oct 2024<\/li>\n<li>Pathogenic roles of EBV strains. Invited speaker at University of Nagoya, Japan, Oct 2024<\/li>\n<li>The Epstein-Barr virus induces the expression of LPAM-1 in B-cells to access the gastrointestinal mucosa-associated lymphoid tissues. 18th International Symposium on EBV and associated diseases, Madison, Wisconsin, July 28-Aug 1, 2018.<\/li>\n<li>The M81 Epstein-Barr Virus associated RNA 2 Enhances CXCL8 production and Spontaneous vius lytic replication in primary B lymphocytes. (Oral Presentation) Nasopharyngeal Carcinoma, Gordon Research Conference, Hong Kong, June 24-29, 2018.<\/li>\n<li>The Epstein-Barr virus BART miRNA cluster of the nasopharyngeal carcinoma-associated M81 strain modulates lytic replication and cell growth in primary B cells. (Oral Presentation) 17th International Symposium on EBV and associated diseases, Z\u00fcrich, Switzerland, Aug 8-12, 2016.<\/li>\n<li>The Epstein-Barr virus BART miRNA cluster of the nasopharyngeal carcinoma-associated M81 strain modulates lytic replication and cell growth in primary B cells. Nasopharyngeal Carcinoma, Gordon Research Conference, Hong Kong, June 26-July 1, 2016.<\/li>\n<li>Spontaneous lytic replication and epitheliotropism define an Epstein-Barr virus strain found in carcinomas. EMBO meeting, Amsterdam, Sep 21-24 , 2013.<\/li>\n<\/ol>\n<\/div>\n<div id=\"tab_laboratory-overview\" class=\"panel entry-content\" role=\"tabpanel\" aria-labelledby=\"tab-laboratory-overview\">\n<h2><strong>Current Research<\/strong><\/h2>\n<p>\u8a73\u7d30\u7814\u7a76\u8cc7\u8a0a\u8acb\u9ede\u9078 https:\/\/wisewind1005.wixsite.com\/tsaimh-ebv\/research<br \/>\u7c21\u4ecb: \u6211\u5011\u5c0d\u65bc\u764c\u75c7\u75c5\u6bd2\uff0c\u7279\u5225\u662fEB\u75c5\u6bd2(EBV,\u53f0\u7063\u5e38\u7a31\u9f3b\u54bd\u764c\u75c5\u6bd2)\u5982\u4f55\u5c0e\u81f4\u4eba\u985e\u4e0a\u76ae\u7d30\u80de\u764c\u6df1\u611f\u8208\u8da3\u3002\u9664\u4e86\u9f3b\u54bd\u764c\uff0c\u4e00\u7a2e\u548cEBV\u7d55\u5c0d\u76f8\u95dc\u7684\u764c\u75c7\uff0c\u76ee\u524d\u4e5f\u767c\u73feEBV\u5728\u80c3\u764c\u3001\u80ba\u764c\u3001\u4e73\u764c\u3001\u5927\u8178\u764c\u3001\u6dcb\u5df4\u764c\u3001\u80f8\u817a\u764c\u7b49\u5404\u985e\u764c\u75c7\uff0c\u751a\u81f3\u591a\u7a2e\u81ea\u9ad4\u514d\u75ab\u75be\u75c5\uff0c\u90fd\u53ef\u5927\u91cf\u767c\u73feEBV\u611f\u67d3\u7684\u8b49\u64da\u3002\u5f88\u53ef\u60dcEBV\u5230\u5e95\u5982\u4f55\u5c0e\u81f4\u9019\u4e9b\u75be\u75c5\u4ecd\u4e0d\u6e05\u695a\u3002<br \/>\u6211\u5011\u5be6\u9a57\u5ba4\u5177\u5099\u5168\u4e16\u754c\u5c0d\u6b64\u75c5\u6bd2\u7814\u7a76\u4e4b\u6700\u5148\u9032\u6280\u8853\uff0c\u7576\u524d\u6211\u5011\u5c07\u4e3b\u529b\u653e\u5728\u6b64\u75c5\u6bd2\u5c0d\u80c3\u764c\u9020\u6210\u4e4b\u6a5f\u5236\u3002\u6211\u5011\u4e5f\u540c\u6642\u7814\u7a76\u4e00\u4e9b\u65b0\u767c\u73fe\u7531\u6b64\u75c5\u6bd2\u5c0e\u81f4\u4e4b\u764c\u75c7\u7a2e\u985e\u53ca\u75be\u75c5\u3002<br \/>\u540c\u6642\uff0c\u6211\u5011\u4e5f\u5617\u8a66\u6539\u9020\u9019\u4e9b\u81f4\u764c\u75c5\u6bd2\u4f7f\u4e4b\u70ba\u6211\u5011\u6240\u7528\u3002\u6211\u5011\u6709\u5c08\u9580\u6280\u8853\u53ef\u4ee5\u53bb\u6539\u9020\u5927\u9ad4\u7a4d\u4e4bDNA\u75c5\u6bd2\u4e26\u4e14\u6210\u529f\u5c07\u4e4b\u9001\u5230\u5bbf\u4e3b\u7d30\u80de\u5167\u3002\u671f\u5f85\u6211\u5011\u80fd\u5c07\u9019\u4e9b\u201d\u58de\u58de\u201d\u7684\u75c5\u6bd2\u8f49\u5316\u8b8a\u6210\u4eba\u985e\u6709\u7528\u7684\u5de5\u5177\u3002\u7aed\u8aa0\u6b61\u8fce\u60a8\u52a0\u5165\u6211\u5011\u4e26\u7528\u7814\u7a76\u75c5\u6bd2\u4f86\u6539\u8b8a\u9019\u500b\u4e16\u754c!<\/p>\n<p><img width=\"1444\" height=\"1500\"\nfetchpriority=\"high\"\ndecoding=\"async\"\nclass=\"alignnone size-full wp-image-802\"\nsrc=\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u5be6\u9a57\u5ba4\u4ecb\u7d39-3-1444x1500-1.jpg\"\nalt=\"\u8521\u660e\u7ff0\u526f\u6559\u6388\u5be6\u9a57\u5ba4\u4ecb\u7d39\u5716\"\nwidth=\"1444\"\nheight=\"1500\"\nsrcset=\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u5be6\u9a57\u5ba4\u4ecb\u7d39-3-1444x1500-1.jpg 1444w,\nhttps:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u5be6\u9a57\u5ba4\u4ecb\u7d39-3-1444x1500-1-289x300.jpg 289w,\nhttps:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u5be6\u9a57\u5ba4\u4ecb\u7d39-3-1444x1500-1-986x1024.jpg 986w,\nhttps:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u5be6\u9a57\u5ba4\u4ecb\u7d39-3-1444x1500-1-768x798.jpg 768w\"\nsizes=\"(max-width: 1444px) 100vw, 1444px\" srcset=\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u5be6\u9a57\u5ba4\u4ecb\u7d39-3-1444x1500-1.jpg 1444w, https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u5be6\u9a57\u5ba4\u4ecb\u7d39-3-1444x1500-1-289x300.jpg 289w, https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u5be6\u9a57\u5ba4\u4ecb\u7d39-3-1444x1500-1-986x1024.jpg 986w, https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u5be6\u9a57\u5ba4\u4ecb\u7d39-3-1444x1500-1-768x798.jpg 768w\" sizes=\"(max-width: 1444px) 100vw, 1444px\" \/><\/p>\n<p>\u8a73\u7d30\u7814\u7a76\u8cc7\u8a0a\u8acb\u9ede\u9078\u00a0https:\/\/wisewind1005.wixsite.com\/tsaimh-ebv\/research<\/p>\n<h2><strong>Laboratory Members<\/strong><\/h2>\n<p>\u7576\u524d\u4eba\u54e1\u53ca\u5148\u524d\u6210\u54e1\uff1ahttps:\/\/wisewind1005.wixsite.com\/tsaimh-ebv\/people<\/p>\n<p>\u7576\u524d\u6210\u54e1\uff1a<br \/>\u535a\u58eb\u751f\uff1a\u5433\u7acb\u8431(Emily), \u6b66\u7389\u53ef\u6021(Zoe)<br \/>\u78a9\u58eb\u751f\uff1a\u5f35\u656c\u6148(Kei), \u912d\u6c0f\u8d8a\u9805(Jade), \u88f4\u7af9\u8587(Vy), \u912d\u7acb\u6674(Sally), \u962e\u7389\u660e\u6052(Minh), \u90b1\u82e0\u5cf0(Mike), \u8521\u7440\u5022(Jessica)<\/p>\n<h2><strong>Laboratory Photos<\/strong><\/h2>\n<div style=\"display:flex; gap:20px; flex-wrap:wrap;\">\n<div style=\"flex:1; min-width:220px;\">\n    <img decoding=\"async\"\n    src=\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u6210\u54e1\u7167-1-1500x842-1.png\"\n    alt=\"\u8521\u660e\u7ff0\u526f\u6559\u6388\u5be6\u9a57\u5ba4\u6210\u54e1\u5408\u7167\"\n    style=\"width:100%; height:auto;\">\n  <\/div>\n<div style=\"flex:1; min-width:220px;\">\n    <img decoding=\"async\"\n    src=\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u5be6\u9a57\u5ba4\u7167\u7247-7-1500x1000-1.jpg\"\n    alt=\"\u8521\u660e\u7ff0\u526f\u6559\u6388\u5be6\u9a57\u5ba4\u7814\u7a76\u74b0\u5883\u7167\u7247\"\n    style=\"width:100%; height:auto;\">\n  <\/div>\n<div style=\"flex:1; min-width:220px;\">\n    <img decoding=\"async\"\n    src=\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u5be6\u9a57\u5ba4\u7167\u7247-5-1500x844-1.jpg\"\n    alt=\"\u8521\u660e\u7ff0\u526f\u6559\u6388\u5be6\u9a57\u5ba4\u7814\u7a76\u8a2d\u5099\u7167\u7247\"\n    style=\"width:100%; height:auto;\">\n  <\/div>\n<div style=\"flex:1; min-width:220px;\">\n    <img decoding=\"async\"\n    src=\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u5be6\u9a57\u5ba4\u7167\u7247-6.jpg\"\n    alt=\"\u8521\u660e\u7ff0\u526f\u6559\u6388\u5be6\u9a57\u5ba4\u7814\u7a76\u60c5\u5f62\u7167\u7247\"\n    style=\"width:100%; height:auto;\">\n  <\/div>\n<\/div>\n<\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":1137,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[26],"tags":[],"class_list":["post-1135","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-full-time-faculty2"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Ming-Han Tsai - \u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \u5fae\u751f\u7269\u53ca\u514d\u75ab\u5b78\u7814\u7a76\u6240<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ming-Han Tsai - \u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \u5fae\u751f\u7269\u53ca\u514d\u75ab\u5b78\u7814\u7a76\u6240\" \/>\n<meta property=\"og:url\" content=\"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/\" \/>\n<meta property=\"og:site_name\" content=\"\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \u5fae\u751f\u7269\u53ca\u514d\u75ab\u5b78\u7814\u7a76\u6240\" \/>\n<meta property=\"article:published_time\" content=\"2025-06-24T06:02:48+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-25T05:47:50+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"1545\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"qqfoodlover@gmail.com\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"qqfoodlover@gmail.com\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"12 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/\"},\"author\":{\"name\":\"qqfoodlover@gmail.com\",\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/#\/schema\/person\/2619eb08157affd191656413dd5acb7f\"},\"headline\":\"Ming-Han Tsai\",\"datePublished\":\"2025-06-24T06:02:48+00:00\",\"dateModified\":\"2026-03-25T05:47:50+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/\"},\"wordCount\":2054,\"image\":{\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai.jpg\",\"articleSection\":[\"Full-time Faculty\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/\",\"url\":\"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/\",\"name\":\"Ming-Han Tsai - \u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \u5fae\u751f\u7269\u53ca\u514d\u75ab\u5b78\u7814\u7a76\u6240\",\"isPartOf\":{\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai.jpg\",\"datePublished\":\"2025-06-24T06:02:48+00:00\",\"dateModified\":\"2026-03-25T05:47:50+00:00\",\"author\":{\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/#\/schema\/person\/2619eb08157affd191656413dd5acb7f\"},\"breadcrumb\":{\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/#primaryimage\",\"url\":\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai.jpg\",\"contentUrl\":\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai.jpg\",\"width\":1200,\"height\":1545},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9801\",\"item\":\"https:\/\/imi.nycu.edu.tw\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Ming-Han Tsai\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/#website\",\"url\":\"https:\/\/imi.nycu.edu.tw\/en\/\",\"name\":\"\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \u5fae\u751f\u7269\u53ca\u514d\u75ab\u5b78\u7814\u7a76\u6240\",\"description\":\"Institute of Microbiology and Immunology, NYTU\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/imi.nycu.edu.tw\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/#\/schema\/person\/2619eb08157affd191656413dd5acb7f\",\"name\":\"qqfoodlover@gmail.com\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/imi.nycu.edu.tw\/en\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/0686754646950c85b2690b10899e5a7a8199231c76f0f3e6052dfb9b447bbace?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/0686754646950c85b2690b10899e5a7a8199231c76f0f3e6052dfb9b447bbace?s=96&d=mm&r=g\",\"caption\":\"qqfoodlover@gmail.com\"},\"sameAs\":[\"https:\/\/imi.nycu.edu.tw\"],\"url\":\"https:\/\/imi.nycu.edu.tw\/en\/author\/qqfoodlovergmail-com\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Ming-Han Tsai - \u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \u5fae\u751f\u7269\u53ca\u514d\u75ab\u5b78\u7814\u7a76\u6240","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/","og_locale":"en_US","og_type":"article","og_title":"Ming-Han Tsai - \u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \u5fae\u751f\u7269\u53ca\u514d\u75ab\u5b78\u7814\u7a76\u6240","og_url":"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/","og_site_name":"\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \u5fae\u751f\u7269\u53ca\u514d\u75ab\u5b78\u7814\u7a76\u6240","article_published_time":"2025-06-24T06:02:48+00:00","article_modified_time":"2026-03-25T05:47:50+00:00","og_image":[{"width":1200,"height":1545,"url":"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai.jpg","type":"image\/jpeg"}],"author":"qqfoodlover@gmail.com","twitter_card":"summary_large_image","twitter_misc":{"Written by":"qqfoodlover@gmail.com","Est. reading time":"12 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/#article","isPartOf":{"@id":"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/"},"author":{"name":"qqfoodlover@gmail.com","@id":"https:\/\/imi.nycu.edu.tw\/en\/#\/schema\/person\/2619eb08157affd191656413dd5acb7f"},"headline":"Ming-Han Tsai","datePublished":"2025-06-24T06:02:48+00:00","dateModified":"2026-03-25T05:47:50+00:00","mainEntityOfPage":{"@id":"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/"},"wordCount":2054,"image":{"@id":"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/#primaryimage"},"thumbnailUrl":"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai.jpg","articleSection":["Full-time Faculty"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/","url":"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/","name":"Ming-Han Tsai - \u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \u5fae\u751f\u7269\u53ca\u514d\u75ab\u5b78\u7814\u7a76\u6240","isPartOf":{"@id":"https:\/\/imi.nycu.edu.tw\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/#primaryimage"},"image":{"@id":"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/#primaryimage"},"thumbnailUrl":"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai.jpg","datePublished":"2025-06-24T06:02:48+00:00","dateModified":"2026-03-25T05:47:50+00:00","author":{"@id":"https:\/\/imi.nycu.edu.tw\/en\/#\/schema\/person\/2619eb08157affd191656413dd5acb7f"},"breadcrumb":{"@id":"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/#primaryimage","url":"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai.jpg","contentUrl":"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u8521\u660e\u7ff0\u526f\u6559\u6388_Ming-Han-Tsai.jpg","width":1200,"height":1545},{"@type":"BreadcrumbList","@id":"https:\/\/imi.nycu.edu.tw\/en\/ming-han-tsai\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9801","item":"https:\/\/imi.nycu.edu.tw\/en\/"},{"@type":"ListItem","position":2,"name":"Ming-Han Tsai"}]},{"@type":"WebSite","@id":"https:\/\/imi.nycu.edu.tw\/en\/#website","url":"https:\/\/imi.nycu.edu.tw\/en\/","name":"\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \u5fae\u751f\u7269\u53ca\u514d\u75ab\u5b78\u7814\u7a76\u6240","description":"Institute of Microbiology and Immunology, NYTU","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/imi.nycu.edu.tw\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/imi.nycu.edu.tw\/en\/#\/schema\/person\/2619eb08157affd191656413dd5acb7f","name":"qqfoodlover@gmail.com","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/imi.nycu.edu.tw\/en\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/0686754646950c85b2690b10899e5a7a8199231c76f0f3e6052dfb9b447bbace?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/0686754646950c85b2690b10899e5a7a8199231c76f0f3e6052dfb9b447bbace?s=96&d=mm&r=g","caption":"qqfoodlover@gmail.com"},"sameAs":["https:\/\/imi.nycu.edu.tw"],"url":"https:\/\/imi.nycu.edu.tw\/en\/author\/qqfoodlovergmail-com\/"}]}},"_links":{"self":[{"href":"https:\/\/imi.nycu.edu.tw\/en\/wp-json\/wp\/v2\/posts\/1135","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/imi.nycu.edu.tw\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/imi.nycu.edu.tw\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/imi.nycu.edu.tw\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/imi.nycu.edu.tw\/en\/wp-json\/wp\/v2\/comments?post=1135"}],"version-history":[{"count":2,"href":"https:\/\/imi.nycu.edu.tw\/en\/wp-json\/wp\/v2\/posts\/1135\/revisions"}],"predecessor-version":[{"id":1743,"href":"https:\/\/imi.nycu.edu.tw\/en\/wp-json\/wp\/v2\/posts\/1135\/revisions\/1743"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/imi.nycu.edu.tw\/en\/wp-json\/wp\/v2\/media\/1137"}],"wp:attachment":[{"href":"https:\/\/imi.nycu.edu.tw\/en\/wp-json\/wp\/v2\/media?parent=1135"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/imi.nycu.edu.tw\/en\/wp-json\/wp\/v2\/categories?post=1135"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/imi.nycu.edu.tw\/en\/wp-json\/wp\/v2\/tags?post=1135"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}