{"id":1228,"date":"2025-06-24T14:39:16","date_gmt":"2025-06-24T06:39:16","guid":{"rendered":"https:\/\/imi.nycu.edu.tw\/chi-hung-lin\/"},"modified":"2026-03-26T10:08:14","modified_gmt":"2026-03-26T02:08:14","slug":"chi-hung-lin","status":"publish","type":"post","link":"https:\/\/imi.nycu.edu.tw\/en\/chi-hung-lin\/","title":{"rendered":"Chi-Hung Lin"},"content":{"rendered":"<div class=\"row\"  id=\"row-1683655672\">\n\n\t<div id=\"col-403921220\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<ul>\n<li>Current position\u00a0 :\u5fae\u751f\u7269\u53ca\u514d\u75ab\u5b78\u7814\u7a76\u6240 \u5408\u8058\u6559\u6388<\/li>\n<li>Expertise : \u7d30\u80de\u751f\u7269\u5b78\u3001\u764c\u75c7\u751f\u7269\u5b78\u3001\u751f\u91ab\u5149\u96fb\u5b78\u3001\u57fa\u56e0\u9ad4\u5b78<\/li>\n<li>Location: \u751f\u7269\u91ab\u5b78\u5927\u6a13(R304)<\/li>\n<li>TEL (office): +886-2-28267270<\/li>\n<li>TEL (lab): +886-2-28267000 ext 65613<\/li>\n<li>E-mail: linch@nycu.edu.tw<\/li>\n<li>Website\uff1a<a href=\"https:\/\/sites.google.com\/view\/chl-lab\/pi\">https:\/\/sites.google.com\/view\/chl-lab\/pi<\/a><\/li>\n<li>ORCID:\u00a0<a href=\"https:\/\/orcid.org\/%200000-0001-5658-9377\">0000-0001-5658-9377<\/a><\/li>\n<\/ul>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-2004486086\" class=\"col medium-6 small-12 large-6\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n<p><img fetchpriority=\"high\" decoding=\"async\" width=\"692\" height=\"1024\"\nsrc=\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u6797\u5947\u5b8f\u6821\u9577-692x1024.jpg\"\nclass=\"attachment-large size-large\"\nalt=\"\u6797\u5947\u5b8f\u6559\u6388\"\nsrcset=\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u6797\u5947\u5b8f\u6821\u9577-692x1024.jpg 692w, https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u6797\u5947\u5b8f\u6821\u9577-203x300.jpg 203w, https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u6797\u5947\u5b8f\u6821\u9577-768x1136.jpg 768w, https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u6797\u5947\u5b8f\u6821\u9577-1038x1536.jpg 1038w, https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/\u6797\u5947\u5b8f\u6821\u9577.jpg 1052w\"\nsizes=\"(max-width: 692px) 100vw, 692px\"><\/p>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n\n\t\t<div class=\"tabbed-content\">\n\t\t\t\n\t\t\t<ul class=\"nav nav-tabs nav-uppercase nav-size-normal nav-left\" role=\"tablist\"><li id=\"tab-professional-experience\" class=\"tab active has-icon\" role=\"presentation\"><a href=\"#tab_professional-experience\" role=\"tab\" aria-selected=\"true\" aria-controls=\"tab_professional-experience\"><span>Professional Experience<\/span><\/a><\/li>\n<li id=\"tab-selected-honors-and-awards\" class=\"tab has-icon\" role=\"presentation\"><a href=\"#tab_selected-honors-and-awards\" tabindex=\"-1\" role=\"tab\" aria-selected=\"false\" aria-controls=\"tab_selected-honors-and-awards\"><span>Selected Honors and Awards<\/span><\/a><\/li>\n<li id=\"tab-publications-and-research-projects\" class=\"tab has-icon\" role=\"presentation\"><a href=\"#tab_publications-and-research-projects\" tabindex=\"-1\" role=\"tab\" aria-selected=\"false\" aria-controls=\"tab_publications-and-research-projects\"><span>Publications and Research Projects<\/span><\/a><\/li>\n<li id=\"tab-laboratory-overview\" class=\"tab has-icon\" role=\"presentation\"><a href=\"#tab_laboratory-overview\" tabindex=\"-1\" role=\"tab\" aria-selected=\"false\" aria-controls=\"tab_laboratory-overview\"><span>Laboratory Overview<\/span><\/a><\/li><\/ul><div class=\"tab-panels\"><div id=\"tab_professional-experience\" class=\"panel active entry-content\" role=\"tabpanel\" aria-labelledby=\"tab-professional-experience\">\n<div class=\"av-special-heading av-1wyde5j-178bec8df35a0d430fe73e96c64f78ce av-special-heading-h2 custom-color-heading blockquote modern-quote avia-builder-el-9 el_before_av_textblock avia-builder-el-first \">\n<div class=\"av-special-heading av-1wyde5j-178bec8df35a0d430fe73e96c64f78ce av-special-heading-h2 custom-color-heading blockquote modern-quote avia-builder-el-9 el_before_av_textblock avia-builder-el-first \">\n<div class=\"av-special-heading av-1xclv8f-a3f0d2cecbec6a4fcaa467b70d690622 av-special-heading-h2 custom-color-heading blockquote modern-quote avia-builder-el-9 el_before_av_textblock avia-builder-el-first \">\n<div class=\"av-special-heading av-1xfg3sb-bf432a71e6108c7bfdf2b1ea53665e9b av-special-heading-h2 custom-color-heading blockquote modern-quote avia-builder-el-9 el_before_av_textblock avia-builder-el-first \">\n<div class=\"av-special-heading av-1w7p69g-2cf129b3989fcea735a4837633aa887b av-special-heading-h3 custom-color-heading blockquote modern-quote avia-builder-el-8 el_before_av_textblock avia-builder-el-first \">\n<h3 class=\"av-special-heading-tag\">\u5b78\u6b77<\/h2>\n<\/div>\n<section class=\"av_textblock_section av-1vai9ac-a42a9586ab999e851c8e074539165582\">\n<div class=\"avia_textblock av_inherit_color\">\n<p>\u7f8e\u570b\u8036\u9b6f\u5927\u5b78\u751f\u7269\u7cfb \/ \u535a\u58eb<\/p>\n<p>\u570b\u7acb\u967d\u660e\u5927\u5b78\u91ab\u5b78\u7cfb \/ \u91ab\u5b78\u58eb<\/p>\n<\/div>\n<\/section>\n<section class=\"av_textblock_section av-1qs3mw4-1c501e8d1010764257f40e882154aeda\">\n<h3 class=\"avia_textblock av_inherit_color\"><span style=\"color: #555555;\">\u73fe\u8077<\/span><\/h2>\n<\/section>\n<section class=\"av_textblock_section av-1lqjpok-796dddc700c4008458e7449a12af92f8\">\n<div class=\"avia_textblock av_inherit_color\">\n<p>\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \/ \u6821\u9577 \/ 2021\/02\u81f3\u4eca<\/p>\n<p>\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \/ \u751f\u7269\u79d1\u6280\u5b78\u7cfb \/ \u6559\u6388 \/ 2020\/02 \u81f3\u4eca<\/p>\n<p>\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78 \/ \u5fae\u751f\u7269\u53ca\u514d\u75ab\u5b78\u7814\u7a76\u6240\/\u5fae\u751f\u7269\u79d1 \/ \u6559\u6388 \/ 2003\/10 \u81f3\u4eca<\/p>\n<h2>\u7d93\u6b77<\/h2>\n<p>\u570b\u7acb\u4ea4\u901a\u5927\u5b78 \u53f0\u7063\u806f\u5408\u5927\u5b78\u7cfb\u7d71 \u526f\u6821\u9577 2020\/02 \u81f3 2021\/01<\/p>\n<p>\u570b\u7acb\u4ea4\u901a\u5927\u5b78 \u667a\u6167\u91ab\u7642\u63a8\u52d5\u4e2d\u5fc3 \u4e3b\u4efb 2020\/02 \u81f3 2021\/01<\/p>\n<p>\u65b0\u5317\u5e02\u653f\u5e9c \u885b\u751f\u5c40 \u5c40\u9577 2014\/12\u81f32018\/12<\/p>\n<p>\u81fa\u5317\u5e02\u653f\u5e9c \u885b\u751f\u5c40 \u5c40\u9577 2010\/12\u81f32014\/12<\/p>\n<p>\u570b\u7acb\u967d\u660e\u5927\u5b78 \u570b\u969b\u4e8b\u52d9\u8655 \u4e3b\u4efb 2010\/08\u81f32010\/12<\/p>\n<p>\u570b\u7acb\u967d\u660e\u5927\u5b78 \u5fae\u751f\u7269\u53ca\u514d\u75ab\u5b78\u7814\u7a76\u6240\/\u5fae\u751f\u7269\u79d1 \u6240\u9577 2007\/08\u81f32010\/08<\/p>\n<p>\u81fa\u5317\u5e02\u7acb\u806f\u5408\u91ab\u9662 \u6559\u7814\u90e8 \u4e3b\u4efb 2006\/03\u81f32010\/12<\/p>\n<p>\u570b\u7acb\u967d\u660e\u5927\u5b78 \u5100\u5668\u4e2d\u5fc3 \u4e3b\u4efb 2005\/03\u81f32010\/07<\/p>\n<\/div>\n<\/section>\n<\/div>\n<div class=\"hr av-1ei2s8b-1570bb28c39f36e084a341106c7c4d20 hr-short avia-builder-el-18 el_after_av_textblock el_before_av_textblock hr-left\"><\/div>\n<\/div>\n<\/div>\n<section class=\"av_textblock_section av-1682wiv-8006e72fe9d03e2941376d8c27411fd8\"><\/section>\n<\/div>\n<section class=\"av_textblock_section av-1682wiv-8006e72fe9d03e2941376d8c27411fd8\"><\/section>\n<\/div>\n<div id=\"tab_selected-honors-and-awards\" class=\"panel entry-content\" role=\"tabpanel\" aria-labelledby=\"tab-selected-honors-and-awards\">\n<h2>\u7372\u734e<\/h2>\n<ul>\n<li>2013\u00a0\u00a0\u00a0 \u570b\u7acb\u967d\u660e\u5927\u5b78\u7b2c\u5341\u5c46\u5091\u51fa\u6821\u53cb<\/li>\n<li>2009\u00a0\u00a0\u00a0 \u884c\u653f\u9662\u5091\u51fa\u79d1\u6280\u8ca2\u737b\u734e<\/li>\n<li>2004\u00a0\u00a0\u00a0 \u884c\u653f\u9662\u570b\u79d1\u6703\u5091\u51fa\u7814\u7a76\u734e<\/li>\n<li>2002\u00a0\u00a0\u00a0 \u4e2d\u83ef\u6c11\u570b\u764c\u75c7\u91ab\u5b78\u6703\u5f90\u5343\u7530\u764c\u75c7\u7814\u7a76\u5091\u51fa\u734e<\/li>\n<\/ul>\n<\/div>\n<div id=\"tab_publications-and-research-projects\" class=\"panel entry-content\" role=\"tabpanel\" aria-labelledby=\"tab-publications-and-research-projects\">\n<div class=\"av-special-heading av-10md8rr-c752fab7bc091682958c7effdda61054 av-special-heading-h2 custom-color-heading blockquote modern-quote avia-builder-el-25 el_after_av_hr el_before_av_textblock \">\n<div class=\"av-special-heading av-119zicf-fe0cbcb596da82d940a795e95a0e6b9a av-special-heading-h2 custom-color-heading blockquote modern-quote avia-builder-el-26 el_after_av_hr el_before_av_textblock \">\n<div class=\"av-special-heading av-119txq3-a91c0104c08c0ee8e169fb4e5def782c av-special-heading-h2 custom-color-heading blockquote modern-quote avia-builder-el-23 el_after_av_hr el_before_av_textblock \">\n<div class=\"av-special-heading av-11avg1g-ab00c5d12c109b6d15890eaff06c5ec5 av-special-heading-h3 custom-color-heading blockquote modern-quote avia-builder-el-18 el_after_av_hr el_before_av_textblock \">\n<h3 class=\"av-special-heading-tag\">\u8ad6\u6587<\/h2>\n<\/div>\n<section class=\"av_textblock_section av-zettb8-23005efd24ce010f5c750ead980247dc\">\n<div class=\"avia_textblock\">\n<ol>\n<li>Forscher P,<strong><u> Lin CH<\/u><\/strong>, and Thompson C. (1992) Novel Form of Growth Cone Motility Involving Site-Directed Actin Filament Assembly. Nature 1992 Jun; 357(6378):515-518.<\/li>\n<li><strong><u>Lin CH<\/u><\/strong> and Forscher P. (1993) Cytoskeletal Remodeling During Growth Cone-Target Interactions. J. Cell Biol. 1993 Jun; 121(6):1369-1383.<\/li>\n<li>Fisher T, <strong><u>Lin CH<\/u><\/strong> and Kaczmarek LK. (1993) The Peptide FMRFa Terminates a Discharge in Aplysia Bag Cell Neurons by Modulating Calcium, Potassium and Chloride Conductances. J. Neurophysiol. 1993 Jun; 69(6):2164-2173.<\/li>\n<li>Azhderian EM, Hefner D, <strong><u>Lin CH<\/u><\/strong>, Kaczmarek LK and Forscher P. (1994) Cyclic AMP Modulates Fast Axonal Transport in Aplysia Bag Cell Neurons By Increasing the Probability of Single Organelle Movement. Neuron 1994 Jun; 12(6):1223-1233.<\/li>\n<li><strong><u>Lin CH<\/u><\/strong>, Thompson CA and Forscher P. (1994) Cytoskeletal reorganization underlying growth cone motility. Cur. Op. Neurobiol. 1994 Oct; 4(5):640-647.<\/li>\n<li><strong><u>Lin CH<\/u><\/strong> and Forscher P. (1995) Growth Cone Advance Is Inversely Proportional to Retrograde F-actin Flow. Neuron 1995 Apr; 14(4):763-771.<\/li>\n<li><strong><u>Lin CH<\/u><\/strong>, Espreafico EM, Mooseker MS and Forscher P. (1996) Myosin Drives Retrograde F-actin Flow in Neuronal Growth Cones. Neuron 1996 Apr; 16(4):769-782.<\/li>\n<li>Thompson CA, <strong><u>Lin CH<\/u><\/strong> and Forscher P. (1996) An Aplysia Cell Adhesion Molecule Associated with Site-Directed Actin Filament Assembly in Neuronal Growth Cones. J. Cell Sci. 1996 Dec; 109 (12):2843-2854.<\/li>\n<li><strong><u>Lin CH<\/u><\/strong> and Forscher P. (1997) Myosin Drives Retrograde F-actin Flow in Neuronal Growth Cones. Bull. 1997 Feb; 192(1):183-185.<\/li>\n<li>You LR, Chen CM, Yeh TS, Tsai TY, Mai RT, <strong><u>Lin CH<\/u><\/strong>, and Wu Lee YH. (1999) Hepatitis C Virus Core Protein Interacts with Cellular Putative RNA Helicase. J. Virol. 1999 Apr; 73(4):2841-2853.<\/li>\n<li>Chen YJ, Ko JY, Chen PJ, Shu CH, Hsu MT, Tsai SF, and <strong><u>Lin CH<\/u><\/strong> *. (1999) Chromosomal Aberrations in Nasopharygeal Carcinoma Analyzed by Comparative Genomic Hybridization. Genes Chromosomes and Cancer 1999 Jun; 25(2):169-175.<\/li>\n<li>Chang HH, <strong><u>Lin CH<\/u><\/strong> and Lo SJ. (1999) Rhodostomin substrates induce platelet transformation without prior inside-out activation signals. Exp. Cell Res. (1999) Aug; 250(2):387-400.<\/li>\n<li>Lian WN, Tsai1 JW, Yu PM, Wu TW, Yang SC, Chau YP, and <strong><u>Lin CH<\/u><\/strong> *. (1999) Targeting of Aminopeptidase N to Bile Canaliculi Correlates with Secretory Activities of the Developing Canalicular Domain. Hepatology 1999 Sep; 30(3):748-760.<\/li>\n<li>Suter DM, Espindola1 FS, <strong><u>Lin CH<\/u><\/strong>, Forscher P, and Mooseker MS. (2000) Localization of Unconventional Myosins V and VI in Neuronal Growth Cones. J. Neurobiol. 2000 Feb; 42(3):370-382.<\/li>\n<li>Chen FD, Chen KY, Ngo FQ, <strong><u>Lin CH<\/u><\/strong>, Tsai ST, Ling TS, Whang-Peng JJ, Edwards AA, Lloyd DC, and Chen WL. (2000) Chromosomal damage in long-term residents of houses contaminated with cobalt-60. Lancet 2000 Feb; 355(9205):726.<\/li>\n<li>Chen YJ, Yeh SH, Chen JT, Wu CC, Hsu MT, Tsai SF, Chen PJ, and <strong><u>Lin CH<\/u><\/strong> *. (2000) Chromosomal Changes and Clonality Relationship Between Primary and Recurrent Hepatocellular Carcinoma Revealed by Comparative Genomic Hybridization. Gastroenterology 2000 Aug;119(2):431-440.<\/li>\n<li>Tsai JW, Liao BY, Huang CC, Hwang WL, Wang DW, Chiou AE, and <strong><u>Lin CH<\/u><\/strong> *. (2000) Applications of optical tweezers and an integrated force measurement module for biomedical research. Proc. SPIE 4082:213-221<\/li>\n<li>Yang SC, Huang CH, Chen NJ, Chou CK and <strong><u>Lin CH<\/u><\/strong> *. (2000) Functional Implication of Human Serine\/Threonine Kinase, hAIK, in Cell Cycle Progression. J. Biomed. Sci. 2000 Nov-Dec; 7(6):484-493.<\/li>\n<li>Kung SH. Wang YC. <strong><u>Lin CH<\/u><\/strong>. Kuo RL. Liu WT. (2000) Rapid diagnosis and quantification of herpes simplex virus with a green fluorescent protein reporter system. Journal of Virological Methods. 2000 Nov; 90(2):205-212.<\/li>\n<li>Chang SN, <strong><u>Lin CH<\/u><\/strong>, and Lin A. (2000) An acidic amino acid cluster regulates nucleolar localization and ribosome assembly of human ribosomal protein L22. FEBS lett. 2000 Oct; 484(1):22-28.<\/li>\n<li><strong><u>\u6797\u5947\u5b8f<\/u><\/strong>\u3001\u8521\u91d1\u543e\uff0c(2000) \u96f7\u5c04\u5149\u9257\u6280\u8853\u5728\u751f\u7269\u4f5c\u7528\u529b\u7814\u7a76\u4e0a\u7684\u61c9\u7528\uff0c\u7269\u7406\u96d9\u6708\u520a\uff0c\u5eff\u4e8c\u5377\u4e94\u671f\u3002<\/li>\n<li>Yang YC, Shyong WY, Chang MS, Chen YJ, <strong><u>Lin CH<\/u><\/strong>, Wang TY, Hsu MT, and Chen ML. (2001) Frequent gain of copy number on the long arm of chromosome 3 in human cervical adenocarcinoma. Cancer Genetics and Cytogenetics 2001 Nov; 31(1):48-53.<\/li>\n<li>Lo PJ, Chen JY, Tang PP, Lin, J, <strong><u>Lin CH<\/u><\/strong>, Su LT, Wu CH, Chen TL, Yang Y, and Wang FF. (2001) Identification of a mouse thiamine transporter gene as a direct transcriptional target of p53. J. Biol. Chem. 2001 Oct; 276(40):37186-37193.<\/li>\n<li>Yen CC, Chen YJ, Chen JT, Hsia JY, Chen PM, Liu JH, Fan FS, Chiou TJ, Wang WS, and <strong><u>Lin CH<\/u><\/strong> *. (2001). Comparative Genomic Hybridization of Esophageal Squamous Cell Carcinoma: Relationship of Chromosomal Aberrations to Disease Progression and Prognosis. Cancer 2001 Dec; 92(11):2769-2777.<\/li>\n<li>Liu WT, Sun JR, <strong><u>Lin CH<\/u><\/strong>, Kuo RL and Kung SH. (2001) An indicator cell assay for detection of human cytomegalovirus bsed on enhanced grenn fluorescence protein. J. Virological Method 2001 Jul; 96(1):85-92.<\/li>\n<li>\u90b1\u5b97\u51f1\u3001\u9322\u6b63\u6d69\u3001\u9023\u5049\u7537\u3001<strong><u>\u6797\u5947\u5b8f<\/u><\/strong>\uff0c(2001) \u5168\u53cd\u5c04\u87a2\u5149\u986f\u5fae\u8853\u65bc\u751f\u7269\u7269\u7406\u7684\u61c9\u7528\uff0c\u7269\u7406\u96d9\u6708\u520a\uff08\u5eff\u56db\u5377\u4e09\u671f436-442\u9801\uff09<\/li>\n<li>Chung YL, Sheu ML, Yang SC, <strong><u>Lin CH<\/u><\/strong>, Yen SH. (2002) Resistance to tamoxifen-induced apoptosis is associated with direct interaction between Her2\/neu and cell membrane estrogen receptor in breast cancer. Int. J. Cancer 2002 Jan; 97(3):306-312.<\/li>\n<li>Wang PH, Shyong WY, <strong><u>Lin CH<\/u><\/strong>, Chen YJ, Li YF, Chao HT, and Yuan CC. (2002) Analysis of genetic aberrations in uterine adenomyosis using comparative genomic hybridization. Anal. Quant. Cytol. Histol. 2002 Feb; 24(1):1-6.<\/li>\n<li>Lin SC, Chen YJ, Kao SY, Hsu MT, <strong><u>Lin CH<\/u><\/strong>, Yang SC, Liu TY and Chang KW. (2002) Chromosomal changes in betal-associated oral squamous cell carcinomas and their relationship to clinical parameters. Oral Oncology 2002 Apr; 38(3):266-273.<\/li>\n<li>Wang AG, Lee CM, Wang YC, <strong><u>Lin CH<\/u><\/strong> and Fann MJ. (2002) Up-regulation of cytochrome oxidase in the retina following optic nerve injury. Exp. Eye Res. 2002 May; 74(5):651-659.<\/li>\n<li>Chen YJ, Chen PJ, Lee MC, Yeh SH, Hsu MT, <strong><u>Lin CH<\/u><\/strong> *. (2002) Chromosomal analysis of hepatic adenoma and focal nodular hyperplasia by comparative genomic hybridization. Genes Chromosomes Cancer. 2002 Oct;35(2):138-43.<\/li>\n<li>Mei-Jie Jou, Shuo-Bin Jou, Hung-Ming Chen, <strong><u>Chi-Hung Lin<\/u><\/strong>, Tsung-I Peng. (2002) Critical Role of Mitochondrial Reactive Oxygen Species Formation in Visible Laser Irradiation-Induced Apoptosis in Rat Brain Astrocytes (RBA-1). J Biomed Sci 2002; 9(6 Pt 1):507-516.<\/li>\n<li>Hsieh HP, Liou JP, Lin YT, Mahindroo N, Chang YJ, Yang YN, Chen SS, Tan UK, Chang CW, Chen TW, <strong><u>Lin CH<\/u><\/strong>, Chang YY and Wang CC. (2003) Structure-Activity and Crystallographic Analysis of Benzophenone Derivatives &#8211; the Potential Anticancer Agents. Bioorg. Med. Chem. Lett. 2003 Jan; 13(1):101-105.<\/li>\n<li>Li WT, Hwang DR, Chen CP, Shen CW, Huang CL, Chen TW, <strong><u>Lin CH<\/u><\/strong>, Chang YL, Chang YY, Lo YK, Tseng HY, Lin CC, Song JS, Chen HC, Chen SJ, Wu SH and Chen CT. (2003) Synthesis and biological evaluation of N-heterocyclic indolyl gloxylamides as orally active anticancer agents. J. Med. Chem. 2003 Apr; 46(9):1706-1715.<\/li>\n<li>Wang WL, Yeh SF, Chang YI, Hsiao SF, Lian WN, <strong><u>Lin CH<\/u><\/strong>, Huang CY, Lin WJ. (2003) PICK1: An anchoring protein that specifically targets PKCalpha to mitochondria selectively upon serum stimulation in NIH 3T3 cells. J Biol Chem. 2003 Sep; 278(39):37705-37712.<\/li>\n<li>Sung YJ, Sung ZL, Ho CL, Lin MT, Wang JS, Yang SC, Chen YJ, and <strong><u>Lin CH<\/u><\/strong> *. (2003) Intercellular calcium waves mediate preferential cell growth toward the wound edge in polarized hepatic cells. Exp. Cell Res. 2003 Jul; 287(2):209-218.<\/li>\n<li>Yen CC, Chen YJ, Lu KH, Hsia JY, Chen JT, Hu CP, Chen PM, Liu JH, Chiou TJ, Wang WS, Yang MH, Chao TC, and <strong><u>Lin CH<\/u><\/strong> *. (2003) Genotypic analysis of esophageal squamous cell carcinoma by molecular cytogenetics and real-time quantitative polymerase chain reaction. International Journal of Oncology 2003 Oct; 23(4):871-881.<\/li>\n<li>Yen MY, Chen YJ, <strong><u>Lin CH<\/u><\/strong>, Wang AG, Wei YH. (2003) Genetic analysis in Leber&#8217;s hereditary optic neuropathy using the comparative genomic hybridization technique. Clin Experiment Ophthalmol. 2003 Oct; 31(5):435-438.<\/li>\n<li>Yang SC, Lin SC, Chiang WF, Yen CY, <strong><u>Lin CH<\/u><\/strong>, Liu SY. (2003) Areca nut extract treatment elicits the fibroblastoid morphological changes, actin re-organization and signaling activation in oral keratinocytes. J Oral Pathol Med. 2003 Nov;32(10):600-5.<\/li>\n<li>Wu TJ, Huang HH, Lan CW, <strong><u>Lin CH<\/u><\/strong>, Hsu FY, Wang YJ. (2004) Studies on the microspheres comprised of reconstituted collagen and hydroxyapatite. Biomaterials. 2004 Feb; 25(4):651-658.<\/li>\n<li>Chang YC, Hsu TL, Lin HH, Chio CC, Chiu AW, Chen NJ, <strong><u>Lin CH<\/u><\/strong>, Hsieh SL. (2004) Modulation of macrophage differentiation and activation by decoy receptor 3. J Leukoc Biol. 2004 Mar; 75(3):486-494.<\/li>\n<li>Jong YJ, Li LH, Tsou MH, Chen YJ, Cheng SH, Wang-Wuu S, Tsai SF, Chen CM, Huang AT, Hsu MT, and <strong><u>Lin CH<\/u><\/strong>*. (2004) Chromosomal CGH abnormalities in early and late onset human breast cancers: correlations with disease progression and p53 mutations. Cancer Genetics and Cytogenetics 2004 Jan 1;148(1):55-65.<\/li>\n<li>Lin CY, Shen YH, Wu SH, <strong><u>Lin CH<\/u><\/strong>, Hwang SM, Tsai YC. (2004) Effect of bismuth subgallate on nitric oxide and prostaglandin E2 production by macrophages. Biochem Biophys Res Commun. 2004 Mar; 315(4):830-835.<\/li>\n<li>Rong-Yaun Shyu, Shun-Yuan Jiang, Yiin-Jeng Jong, Kuo-Chen Cheng, <strong><u>Chi-Hung Lin<\/u><\/strong>, Jyh-Cherng Yu, Ming-Fang Wu, Tzu-Ming Chang. (2004) Establishment and Characterization of a Human Gastric Carcinoma Cell Line TMC-1. Cells Tissues Organs. 2004;177(1):37-46.<\/li>\n<li>Lin MW, Lee DD, <strong><u>Lin CH<\/u><\/strong>, Huang CY, Wong CK, Chang YT, Liu HN, Hsiao KJ, Tsai SF. (2005) Suggestive linkage of familial primary cutaneous amyloidosis to a locus on chromosome 1q23. Br J Dermatol. 2005 Jan; 152(1):29-36.<\/li>\n<li>Jeng-Kai Jiang, Yann-Jang Chen, <strong><u>Chi-Hung Lin<\/u><\/strong>, I-Ting Yu, Jen-Kou Lin. (2005) Genetic Changes and Clonality Relationship between Primary Colorectal Cancers and Their Pulmonary Metastases \u2013 An Analysis by Comparative Genomic Hybridization. Genes, Chromosomes &amp; Cancer 2005 May; 43(1):25-36.<\/li>\n<li>Yen CC, Chen YJ, Pan CC, Lu KH, Chen PC, Hsia JY, Chen JT, Wu YC, Hsu WH, Wang LS, Huang MH, Huang BS, Hu CP, Chen PM, <strong><u>Lin CH<\/u><\/strong> *. (2005) Copy number changes of target genes in chromosome 3q25.3-qter of esophageal squamous cell carcinoma: TP63 is amplified in early carcinogenesis but down-regulated as disease progressed. World J Gastroenterol. 2005 Mar 7; 11(9):1267-72.<\/li>\n<li>Chung-Lan Kao, Shih-Hwa Chiou, Donald Ming-Tak Ho, Yann-Jang Chen, Ren-Shyan Liu, Chih-Wen Lo, Fu-Ting Tsai, <strong><u>Chi-Hung Lin<\/u><\/strong>, Hung-Hai Ku, Shang-Ming Yu, Tai-Tong Wong. (2005) Elevation of Plasma and Cerebral Spinal Fluid Osteopontin levels in Patients with Atypical Teratoid\/Rhabdoid Tumor. Am J Clin Pathol. 2005 Feb;123(2):297-304.<\/li>\n<li>Shi-Wei Chu, Shih-Peng Tai, Chia-Lin Ho, <strong><u>Chi-Hung Lin<\/u><\/strong>, and Chi-Kuang Sun. (2005) High-Resolution Simultaneous Three-Photon Fluorescence and Third-Harmonic-Generation Microscopy. Microscopy research and technique. 2005 Mar; 66(4):193-197.<\/li>\n<li>Sun DS, Lo SJ, <strong><u>Lin CH<\/u><\/strong>, Yu MS, Huang CY, Chen YF, Chang HH. (2005) Calcium oscillation and phosphatidylinositol 3-kinase positively- regulate integrin \u03b1IIb\u03b23-mediated outside-in signaling. J Biomed Sci. 2005; 12(2):321-333.<\/li>\n<li>Sun DS, Lo SJ, Tsai WJ, <strong><u>Lin CH<\/u><\/strong>, Yu MS, Chen YF, Chang HH. (2005) PI3-kinase is essential for ADP-stimulated integrin alpha(IIb)beta(3)-mediated platelet calcium oscillation, implications for P2Y receptor pathways in integrin alpha(IIb)beta(3)-initiated signaling cross-talks. J Biomed Sci. 2005 Dec 12(6):937-948.<\/li>\n<li>Tu LC, Chen CS, Hsiao IC, Chern JW, <strong><u>Lin CH<\/u><\/strong>, Shen YC, Yeh SF. The beta-carboline analog Mana-Hox causes mitotic aberration by interacting with DNA. Chem Biol. 2005 Dec;12(12):1317-24.<\/li>\n<li>Wei-Nan Lian, Tzu-Wei Wu, Ro-Lan Dao, Yann-Jang Chen, and<strong><u> Chi-Hung Lin<\/u><\/strong>*. (2006) Deglycosylation of Na,K-ATPase causes the basolateral protein to undergo apical targeting in polarized hepatic cells. Journal of Cell Science 2006 Jan; 119(1):11-22.<\/li>\n<li>Ren-In You, Mei-Chieh Chen, Hsei-Wei Wang, Yang-Chieh Chou, <strong><u>Chi-Hung Lin<\/u><\/strong>, and Shie-Liang Hsieh. (2006) Inhibition of Lymphotoxin-B Receptor\u2013Mediated Cell Death by Survivin-#Ex3. Cancer Res. 2006 Mar; 66(6):3051-3061.<\/li>\n<li>Chia-Fen Hsieh, Bo-Jui Chang, Chyi-Huey Pai, Hsuan-Yi Chen, Jin-Wu Tsai, Yung-Hsiang Yi, Yi-Ting Chiang, Da-Wei Wang, Sien Chi, Long Hsu, and <strong><u>Chi-Hung Lin<\/u><\/strong> *. (2006) Stepped Changes Of Monovalent Ligand-Binding Force During Ligand-Induced Clustering Of Integrin aIIBb3. Journal of Biological Chemistry. 2006 Sep; 281(35):25466-25474.<\/li>\n<li>Yang TP, Chang TY, <strong><u>Lin CH<\/u><\/strong>, Hsu MT, Wang HW. (2006) ArrayFusion: a web application for multi-dimensional analysis of CGH, SNP and microarray data. Bioinformatics. 2006 Aug; 22 (21) : 2697\u20132698.<\/li>\n<li>Ruei-Yu He, Guan-Liang Chang, Hua-Lin Wu, <strong><u>Chi-Hung Lin<\/u><\/strong>, Kuo-Chih Chiu, Yuan-Deng Su, and Shean-Jen Chen. (2006) Enhanced live cell membrane imaging using surface plasmon-enhanced total internal reflection fluorescence microscopy. Optics Express. 2006 Oct; 14(20) 9307-9316.<\/li>\n<li>Wei-Nan Lian, Cheng-Hung Chang, Yin-Jhen Chen, Ro-Lan Dao, Yun-Cin Luo, Jun-Yi Chien, Shih-Lian Hsieh and <strong><u>Chi-Hung Lin<\/u><\/strong> *. (2007) Intracellular delivery can be achieved by bombarding cells or tissues with accelerated molecules or bacteria without the need for carrier particles. Experimental Cell Research. 2007 Jan; 313(1):53-64.<\/li>\n<li>Jia-Fwu Shyu, Chung Shih, Chiung-Ying Tseng, <strong><u>Chi-Hung Lin<\/u><\/strong>, Der-Tzong Sun, Hsiao-Tung Liu, Hui-Chu Tsung, Tien-Hua Chen, Ru-Band Lu. (2007) Calcitonin induces podosome disassembly and detachment of osteoclasts by modulating Pyk2 and Src activities. Bone. 2007 May; 40(5):1329-1342.<\/li>\n<li>Shang-Ling Liu, Artashes Karmenyan, Ming-Tzo Wei, Chun-Chieh Huang, <strong><u>Chi-Hung Lin<\/u><\/strong>, and Arthur Chiou. (2007) Optical forced oscillation for the study of lectin-glycoprotein interaction at the cellular membrane of a Chinese hamster ovary cell. Optics Express 2007 Mar; 15(5):2713-2723.<\/li>\n<li>Shi-Wei Chu, Shih-Peng Tai, Chi-Kuang Sun and <strong><u>Chi-Hung Lin<\/u><\/strong>. (2007) Selective imaging in second-harmonic-generation microscopy by polarization manipulation. Appl. Phys. Lett. 2007 Sep; 91:103903.<\/li>\n<li>Li-Jen Su, Ching-Wei Chang, Yu-Chung Wu, Kuang-Chi Chen, Chien-Ju Lin, Shu-Ching Liang, <strong><u>Chi-Hung Lin<\/u><\/strong>, Jacqueline Whang-Peng, Shih-Lan Hsu, Chen-Hsin Chen and Chi-Ying F Huang. (2007) Selection of DDX5 as a novel internal control for Q-RT-PCR from microarray data using a block bootstrap re-sampling scheme. BMC Genomics 2007 Jun; 8:140.<\/li>\n<li>Yen CC, Liang SC, Jong YJ, Chen YJ, <strong><u>Lin CH<\/u><\/strong>, Chen YM, Wu YC, Su WC, Huang CY, Tseng SW, Whang-Peng J. (2007) Chromosomal aberrations of malignant pleural effusions of lung adenocarcinoma: Different cytogenetic changes are correlated with genders and smoking habits. Lung Cancer 2007 Sep; 57(3):292-301.<\/li>\n<li>Chen CY, Ping YH, Lee HC, Chen KH, Lee YM, Chan YJ, Lien TC, Jap TS, <strong><u>Lin CH<\/u><\/strong>, Kao LS, Chen YM. (2007) Open reading frame 8a of the human severe acute respiratory syndrome coronavirus not only promotes viral replication but also induces apoptosis. J Infect Dis. 2007 Aug; 196(3):405-415.<\/li>\n<li>Shi-Wei Chu, Shih-Peng Tai, Ming-Che Chan, Chi-Kuang Sun, I-Ching Hsiao, <strong><u>Chi-Hung Lin<\/u><\/strong>, Yung-Chih Chen, and Bai-Ling Lin. (2007) Thickness dependence of optical second harmonic generation in collagen fibrils. Optics Express. 2007 Sep; 15(19):12005-12010.<\/li>\n<li>Wu JW, Lin LC, Hung SC, <strong><u>Lin CH<\/u><\/strong>, Chi CW, Tsai TH. (2008) Hepatobiliary excretion of silibinin in normal and liver cirrhotic rats. Drug Metab Dispos. 2008 Mar 36(3):589.<\/li>\n<li>Jen CH, Yang TP, Tung CY, Su SH, <strong><u>Lin CH<\/u><\/strong>, Hsu MT, Wang HW. (2008) Signature Evaluation Tool (SET): a Java-based tool to evaluate and visualize the sample discrimination abilities of gene expression signatures. BMC Bioinformatics. 2008 Jan 28;9(1):58<\/li>\n<li>Tzeng WS, Wu RH, Chang SC, Chou CK, Lin CY, Chen JJ, Yang SC, <strong><u>Lin CH<\/u><\/strong>. (2008) Ionic versus nonionic contrast media solvents used with an epirubicin-based agent for transarterial chemoembolization of hepatocellular carcinoma. J Vasc Interv Radiol. 2008 Mar;19(3):342-50.<\/li>\n<li>Chang TY, Li YY, Jen CH, Yang TP,<strong><u> Lin CH<\/u><\/strong>, Hsu MT, Wang HW. (2008) EasyExon&#8211;a Java-based GUI tool for processing and visualization of Affymetrix exon array data. BMC Bioinformatics. 2008 Oct 14;9:432.<\/li>\n<li>Yi YH, Ho PY, Chen TW, Lin WJ, Gukassyan V, Tsai TH, Wang DW, Lew TS, Tang CY, Lo SJ, Chen TY, Kao FJ, <strong><u>Lin CH<\/u><\/strong> *. (2009) Membrane targeting and coupling of NHE1\/integrinalpha IIbbeta 3\/NCX1 by lipid rafts following integrin-ligand interactions trigger Ca2+ oscillations. J Biol Chem. 2009 Feb; 284(6):3855-3864.<\/li>\n<li>Wu MF, Yang CY, Lin TL, Wang JT, Yang FL, Wu SH, Hu BS, Chou TY, Tsai MD, <strong><u>Lin CH<\/u><\/strong>, Hsieh SL. (2009) Humoral Immunity against Capsule Polysaccharide Protects the Host from magA+ Klebsiella pneumoniae-Induced Lethal Disease by Evading Toll-Like Receptor 4 Signaling. Infection and Immunity, Feb. 2009, 77(2):615-621<\/li>\n<li>Chiang YL, <strong><u>Lin CH<\/u><\/strong>, Yen MY, Su YD, Chen SJ, Chen HF. (2009) Innovative antimicrobial susceptibility testing method using surface plasmon resonance. Biosens Bioelectron. 2009 Mar 15; 24(7):1905-10.<\/li>\n<li>Kuo KT, Wang HW, Chou TY, Hsu WH, Hsu HS, <strong><u>Lin CH<\/u><\/strong>, Wang LS. (2009) Prognostic role of PGE2 receptor EP2 in esophageal squamous cell carcinoma. Ann Surg Oncol. 2009 Feb;16(2):352-60.<\/li>\n<li>Wong FH, Huang CY, Su LJ, Wu YC, Lin YS, Hsia JY, Tsai HT, Lee SA, <strong><u>Lin CH<\/u><\/strong>, Tzeng CH, Chen PM, Chen YJ, Liang SC, Lai JM, Yen CC. (2009) Combination of microarray profiling and protein-protein interaction databases delineates the minimal discriminators as a metastasis network for esophageal squamous cell carcinoma. Int J Oncol. 2009 Jan;34(1):117-128.<\/li>\n<li>Tung CY, Jen CH, Hsu MT, Wang HW, <strong><u>Lin CH<\/u><\/strong>*. (2009) A novel regulatory event-based gene set analysis method for exploring global functional changes in heterogeneous genomic data sets. BMC Genomics. 2009 Jan 16; 10(1):26.<\/li>\n<li>Hsing-Wen Wang, Jeng-Kai Jiang, <strong><u>Chi-Hung Lin<\/u><\/strong>, Guang-Jie Huang, and Jia-Sin Yu. (2009) Diffuse reflectance spectroscopy detects increased hemoglobin concentration and decreased oxygenation during colon carcinogenesis from normal to malignant tumors. Opt Express. 2009 Feb 16; 17(4):2805-2817.<\/li>\n<li>Lu KH, Chen YW, Tsai PH, Tsai ML, Lee YY, Chiang CY, Kao CL, Chiou SH,Ku HH, <strong><u>Lin CH<\/u><\/strong>, Chen YJ. (2009) Evaluation of radiotherapy effect in resveratrol-treated medulloblastoma cancer stem-like cells. Child Nerv Syst. 2009 May;25(5):543-50. doi: 10.1007\/s00381-009-0826-6. Epub 2009 Feb 19.<\/li>\n<li>Ting-Ting Liu, You-Hsuan Lin, Chia-Sui Hung, Tian-Jiun Liu, Yu Chen, Yung-Ching Huang, Tsung-Heng Tsai, Huai-Hsien Wang, Da-Wei Wang, Juen-Kai Wang, Yuh-Lin Wang and <strong><u>Chi-Hung Lin<\/u><\/strong> *. (2009) A high speed detection platform based on surface-enhanced Raman scattering for monitoring antibiotic-induced chemical changes in bacteria cell wall. PLoS ONE 2009 May;4(5):e5470.<\/li>\n<li>Wu YT, Huang CM, Lin CC, Ho WA, Lin LC, Chiu TF, Tarng DC, <strong><u>Lin CH<\/u><\/strong>, Tsai TH. (2009) Determination of melamine in rat plasma, liver, kidney, spleen, bladder and brain by liquid chromatography-tandem mass spectrometry. J Chromatogr A. 2009 May; (1216):7595\u20137601.<\/li>\n<li>Yen CC, Chen WM, Chen TH, Chen WY, Chen PC, Chiou HJ, Hung GY, Wu HT, Wei CJ, Shiau CY, Wu YC, Chao TC, Tzeng CH, Chen PM, <strong><u>Lin CH<\/u><\/strong>, Chen YJ, Fletcher JA. (2009) Identification of chromosomal aberrations associated with disease progression and a novel 3q13.31 deletion involving LSAMP gene in osteosarcoma. Int J Oncol. 2009 Oct;35(4):775-788.<\/li>\n<li>Hong-Wen Liu, Yun-Cin Luo, Chia-Lin Ho, and <strong><u>Chi-Hung Lin<\/u><\/strong> *. (2009) Locomotion guidance by extracellular matrix is adaptive and can be restored by a transient change in Ca2+ level. PLoS One. 2009 Oct 5;4(10):e7330.<\/li>\n<li>Lin WJ, Yang CY, Lin YC, Tsai MC, Yang CW, Tung CY, Ho PY, Kao FJ, <strong><u>Lin CH<\/u><\/strong> *. (2010) Phafin2 modulates the structure and function of endosomes by a Rab5-dependent mechanism. Biochem Biophys Res Commun. 2010 Jan 1;391:1043\u20131048.<\/li>\n<li>Wu YT, Huang CM, Lin CC, Ho WA, Lin LC, Chiu TF, Tarng DC, <strong><u>Lin CH<\/u><\/strong>, Tsai TH. (2010) Oral bioavailability, urinary excretion and organ distribution of melamine in Sprague-Dawley rats by high-performance liquid chromatography with tandem mass spectrometry. J Agr Food Chem. 2010 Jan 13;58(1):108-111.<\/li>\n<li>Chen CY, Anderson BO, Lo SS, Lin CH, Chen HM. (2010) Methicillin-Resistant Staphylococcus aureus Infections May Not Impede the Success of Ultrasound-Guided Drainage of Puerperal Breast Abscesses. J Am Coll Surg. 2010 Feb;210(2):148-154.<\/li>\n<li>Su PT, Yen PW, Wang SH, <strong><u>Lin CH<\/u><\/strong>, Chiou A, Syu WJ. (2010) Factors affecting daughter cells&#8217; arrangement during the early bacterial divisions. PLoS One. 2010 Feb 10;5(2):e9147.<\/li>\n<li>Li WT, Hwang DR, Song JS, Chen CP, Chuu JJ, Hu CB, Lin HL, Huang CL, Huang CY, Tseng HY, Lin CC, Chen TW, <strong><u>Lin CH<\/u><\/strong>, Wang HS, Shen CC, Chang CM, Chao YS, Chen CT. (2010) Synthesis and biological activities of 2-amino-1-arylidenamino imidazoles as orally active anticancer agents. J Med Chem. 2010 Mar 25;53(6):2409-2417.<\/li>\n<li>Hsieh CC, Kuo YH, Kuo CC, Chen LT, Cheung CHA, Chao TY, <strong><u>Lin CH<\/u><\/strong>, Pan WY, Chang CY, Chien SC, Chen TW, Lung CC, Chang JY. (2010) Chamacypanone C, a novel skeleton microtubule inhibitor, with anticancer activity by trigger caspase 8-Fas\/FasL dependent apoptotic pathway in human cancer cells. Biochem Pharmacol 2010 May 1; 79(9):1261-1271.<\/li>\n<li>Yang CY, <strong><u>Lin CH<\/u><\/strong>, Jiang JK. (2010) Effects of motivational enhancement therapy on readiness to change MDMA and methamphetamine use behaviors in Taiwanese adolescents. J Surg Oncol. 2010 Aug 1;102(2):196-197.<\/li>\n<li>Chen CF, Hsu EC, Lin KT, Tu PH, Chang HW, Lin CH, Chen YJ, Gu DL, <strong><u>Lin CH<\/u><\/strong>, Wu JY, Chen YT, Hsu MT, Jou YS. (2010) Overlapping high-resolution copy number alterations in cancer genomes identified putative cancer genes in hepatocellular carcinoma. Hepatology. 2010 Nov; 52(5):1690-1701.<\/li>\n<li>Pang TL, Chen FC, Weng YL, Liao HC, Yi YH, Ho CL, <strong><u>Lin CH<\/u><\/strong>, Chen MY. (2010) Costars, a Dictyostelium protein similar to the C-terminal domain of STARS, regulates the actin cytoskeleton and motility. J Cell Sci. 2010 Nov 1;123(Pt 21):3745-3755.<\/li>\n<li>Hu CB, Chen CP, Yeh TK, Song JS, Chang CY, Chuu JJ, Tung FF, Ho PY,Chen TW, <strong><u>Lin CH<\/u><\/strong>, Wang MH, Chang KY, Huang CL, Lin HL, Li WT, Hwang DR, Chern JH, Hwang LL, Chang JY, Chao YS, Chen CT. (2011) BPR0C261 is a novel orally active antitumor agent with antimitotic and anti-angiogenic activities. Cancer Sci. 2011 Jan;102(1):182-191.<\/li>\n<li>Shiau CK, Gu DL, Chen CF, <strong><u>Lin CH<\/u><\/strong>, Jou YS. (2011) IGRhCellID: integrated genomic resources of human cell lines for identification. Nucleic Acids Res. 2011 Jan;39(Database issue):D520-4.<\/li>\n<li>Yang JY, Cheng HW, Chen Y, Li Y, <strong><u>Lin CH<\/u><\/strong>, Lu KL. (2011) Hydrothermally roughened surface-enhanced Raman scattering-active substrates with low background signals for chemical sensing application. J Nanosci Nanotechnol. 2011 Mar;11(3):2012-2017.<\/li>\n<li>Shih YR, Tseng KF, Lai HY, <strong><u>Lin CH<\/u><\/strong>, Lee OK. (2011) Matrix stiffness regulation of integrin-mediated mechanotransduction during osteogenic differentiation of human mesenchymal stem cells. J Bone Miner Res. 2011 Apr;26(4):730-738.<\/li>\n<li>Yen CC, Tsao YP, Chen PC, Wu YC, Liu JH, Pan CC, Liu CY, Tzeng CH, Chen PM, Chen YJ,<strong><u> Lin CH<\/u><\/strong>, Hsu WH. (2011) PML protein as a prognostic molecular marker for patients with esophageal squamous cell carcinomas receiving primary surgery. J Surg Oncol. 2011 Jun;103(8):761-767.<\/li>\n<li>Lin CC, Chen LC, Tseng VS, Yan JJ, Lai WW, Su WP, <strong><u>Lin CH<\/u><\/strong>, Huang CY, Su WC. (2011) Malignant pleural effusion cells show aberrant glucose metabolism gene expression. Eur Respir J. 2011 Jun; 37(6):1453-65<\/li>\n<li>Ting-Yu Liu, Kun-Tong Tsai, Huai-Hsien Wang, Yu Chen, Yu-Hsuan Chen, Yuan-Chun Chao, Hsuan-Hao Chang, <strong><u>Chi-Hung Lin<\/u><\/strong>, Juen-Kai Wang &amp; Yuh-Lin Wang. (2011) Functionalized arrays of Raman-enhancing nanoparticles for capture and culture-free analysis of bacteria in human blood. Nature Communications 2, Article number:538 (15 November 2011)<\/li>\n<li>Wen-Jie Lin, Chih-Yung Yang, Li-Li Li , Yung-Hsiang Yi , Ke-Wei Chen, Ying-Chih Lin, Chin-Chun Liu, <strong><u>Chi-Hung Lin<\/u><\/strong> *. (2012). Lysosomal targeting of phafin1 mediated by Rab7 induces autophagosome formation. Biochem Biophys Res Commun. 2012 Jan 6;417(1):35-42<\/li>\n<li>Kau S, Shiau CK, Gu DL, Ho CM, Su WH, Chen CF, <strong><u>Lin CH<\/u><\/strong>, Jou YS. (2012) NSCLC: integrated genomic database of non-small cell lung cancer. Nucleic Acids Res. 2012 Jan;40(Database issue):D972-7.<\/li>\n<li>Li WT, Hwang DR, Song JS, Chen CP, Chen TW, <strong><u>Lin CH<\/u><\/strong>, Chuu JJ, Lien TW,Hsu TA, Huang CL, Tseng HY, Lin CC, Lin HL, Chang CM, Chao YS, Chen CT. (2012) Synthesis and biological evaluation of 2-amino-1-thiazolyl imidazoles as orally active anticancer agents. Invest New Drugs. 2012 Feb;30(1):164-175.<\/li>\n<li>Yung-Hsiang Yi, Yu-Sun Chang, <strong><u>Chi-Hung Lin<\/u><\/strong>, Tien-Shen Lew, Chih-Yung Tang, Wei-Lien Tseng,Ching-Ping Tseng, and Szecheng J. Lo. (2012). Integrin-mediated membrane blebbing is dependent on sodium-proton exchanger 1 and sodium-calcium exchanger 1 activity. J Biol Chem. 2012 Mar 23;287(13):10316-10324<\/li>\n<li>Lee PY, Chien Y, Chiou GY, <strong><u>Lin CH<\/u><\/strong>, Chiou CH, Tarng DC. (2012) Induced pluripotent stem cells without c-Myc attenuate acute kidney injury via downregulating the signaling of oxidative stress and inflammation in ischemia-reperfusion rats. Cell Transplant. 2012;21(12):2569-2585.<\/li>\n<li>Chen HP, Jiang JK, Chen CY, Chou TY, Chen YC, Chang YT, Lin SF, Chan CH, Yang CY, <strong><u>Lin CH<\/u><\/strong>, Lin JK, Cho WL, Chan YJ. (2012) Human cytomegalovirus preferentially infects the neoplastic epithelium of colorectal cancer: a quantitative and histological analysis. J Clin Virol. 2012 Jul;54(3):240-244.<\/li>\n<li>Kuo YJ, Tsuang FY, Sun JS, <strong><u>Lin CH<\/u><\/strong>, Chen CH, Li JY, Huang YC, Chen WY, Yeh CB, Shyu JF. (2012) Calcitonin inhibits SDCP-induced osteoclast apoptosis and increases its efficacy in a rat model of osteoporosis. PLoS One. 2012;7(7):e40272.<\/li>\n<li>Chin-Yau Chen, Yan-Zhong Chen, Hsueh-Neng Pu, Chien-Ho Tsai, Wei-Ting Chen, <strong><u>Chi-Hung Lin<\/u><\/strong>*. (2012) Bacteriology of acute appendicitis and its implication for the use of prophylactic antibiotics. Surg Infect (Larchmt). 2012 Dec;13(6):383-390.<\/li>\n<li>Cheng S, Lin LC, <strong><u>Lin CH<\/u><\/strong>, Tsai TH. (2013) Comment on Pharmacokinetics and urine metabolite identification of dehydroevodiamine in the rat: from Boymia ruticarpa A. Juss. to Tetradium ruticarpum (A. Juss.) T.G. Hartley. J Agr Food Chem. 2013 Jan 16;61(2):472.<\/li>\n<li>Chia-Lin Ho, Chih-Yung Yang, Wen-Jie Lin, <strong><u>Chi-Hung Lin<\/u><\/strong> *. (2013) Ecto-Nucleoside Triphosphate Diphosphohydrolase 2Modulates Local ATP-Induced Calcium Signaling in Human HaCaT Keratinocytes. PLoS One. 2013 Mar 11;8(3):e57666.<\/li>\n<li>Chih-Sin Hsu, Chien-Yi Tung, Chih-Yung Yang, <strong><u>Chi-Hung Lin<\/u><\/strong> *. (2013) Response to Stress in Early Tumor Colonization Modulates Switching of CD133-Positive and CD133-Negative Subpopulations in a Human Metastatic Colon Cancer Cell Line, SW620. PLoS One. 2013 Apr 5;8(4):e61133.<\/li>\n<li>Hou ML, Chang LW, Chiang CJ, Tsuang YH, <strong><u>Lin CH<\/u><\/strong>, Tsai TH. (2013) Pharmacokinetics of di-isononyl phthalate in freely moving rats by UPLC-MS\/MS. Int J Pharmaceut. 2013 Jun 25;450(1-2):36-43.<\/li>\n<li>Hsueh TY, Wu YT, Lin LC, Chiu AW, <strong><u>Lin CH<\/u><\/strong>, Tsai TH. (2013) Herb-Drug Interaction of Epimedium sagittatum (Sieb. et Zucc.) Maxim Extract on the Pharmacokinetics of Sildenafil in Rats. Molecules. 2013 Jun 21;18(6):7323-7335.<\/li>\n<li>Li WT, Yeh TK, Song JS, Yang YN, Chen TW, <strong><u>Lin CH<\/u><\/strong>, Chen CP, Shen CC, Hsieh CC, Lin HL, Chao YS, Chen CT. (2013) BPR0C305, an orally active microtubule-disrupting anticancer agent. Anti-cancer Drugs. 2013 Nov;24(10):1047-1057.<\/li>\n<li>Huang HL, Yang WY, Pu HF, Tsai TH, <strong><u>Lin CH<\/u><\/strong>, Chen NJ, Tarng DC. (2013) Kr\u00fcppel-like factor 5 associates with melamine-cyanurate crystal-induced nephritis in rats. Nephrol Dial Transplant. 2013 Oct;28(10):2477-83.<\/li>\n<li>Tsai PJ, Wang HS, <strong><u>Lin CH<\/u><\/strong>, Weng ZC, Chen TH, Shyu JF. (2014) Intraportal injection of insulin-producing cells generated from human bone marrow mesenchymal stem cells decreases blood glucose level in diabetic rats. Endocr Res. 2014 Jan; 39(1):26-33<\/li>\n<li>Chiang WC, Ko PC, Chang AM, Chen WT, Liu SS, Huang YS, Chen SY, Lin CH, Cheng MT, Chong KM, Wang HC, Yang CW, Liao MW, Wang CH, Chien YC, <strong><u>Lin CH<\/u><\/strong>, Liu YP, Lee BC, Chien KL, Lai MS, Ma MH. (2014) Bystander-initiated CPR in an Asian metropolitan: Does the socioeconomic status matter? Resuscitation. 2014 Jan;85(1):53-58<\/li>\n<li>Yen CC, Hsiao CD, Chen WM, Wen YS, Lin YC, Chang TW, Yao FY, Hung SC, Wang JY, Chiu JH, Wang HW, <strong><u>Lin CH<\/u><\/strong>, Chen TH, Chen PC, Liu CL, Tzeng CH, Fletcher JA. (2014) Cytotoxic effects of 15d-PGJ2 against osteosarcoma through ROS-mediated AKT and cell cycle inhibition. Oncotarget. 2014 Feb; 5(3):716-725<\/li>\n<li>Hwang WL, Jiang JK, Yang SH, Huang TS, Lan HY, Teng HW, Yang CY, Tsai YP, <strong><u>Lin CH<\/u><\/strong>, Wang HW, Yang MH. (2014) MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells. Nat Cell Biol. 2014 Feb 23;16(3):268-280.<\/li>\n<li>Hou ML, Chang LW, <strong><u>Lin CH<\/u><\/strong>, Lin LC, Tsai TH. (2014) Determination of bioactive components in Chinese herbal formulae and pharmacokinetics of rhein in rats by UPLC-MS\/MS. Molecules. 2014 Apr 2;19(4):4058-4075.<\/li>\n<li>Hong-Wen Liu, Chia-Ping Lin, Yi-Jia Liou, Kuo-Wei Hsu,Jung-Yen Yang, <strong><u>Chi-Hung Lin<\/u><\/strong>*. (2014) NBT-II cell locomotion is modulated by restricting the size of focalcontacts and is improved through EGF and ROCK signaling. The International Journal of Biochemistry &amp; Cell Biology 51 (April, 2014) 131\u2013141<\/li>\n<li>Cheng S, Lin LC, <strong><u>Lin CH<\/u><\/strong>, Tsai TH. (2014) Comparative oral bioavailability of geniposide following oral administration of geniposide, Gardenia jasminoides Ellis fruits extracts and Gardenia herbal formulation in rats. J Pharm Pharmacol. 2014 May;66(5):705-712.<\/li>\n<li>Ju-Yu Tseng, Chih-Yung Yang, Shu-Ching Liang, Ren-Shyan Liu, Shung-Haur Yang, Jen-Kou Lin,Yuh-Min Chen, Yu-Chung Wu, Jeng-Kai Jiang, and <strong><u>Chi-Hung Lin<\/u><\/strong>*. (2014) Interleukin-17A Modulates Circulating Tumor Cells in Tumor Draining Vein of Colorectal Cancers and Affects Metastases. Clin Cancer Res. 2014 Jun 1;20(11):2885-2897.<\/li>\n<li>Chih-Yung Yang, Ruey-Hwa Lu, Chien-Hsing Lin, Chih-Hung Jen, Chien-Yi Tung, Shung-Haur Yang, Jen-Kou Lin, Jeng-Kai Jiang, <strong><u>Chi-Hung Lin<\/u><\/strong> *. (2014) Single Nucleotide Polymorphisms Associated with Colorectal Cancer Susceptibility and Loss of Heterozygosity in a Taiwanese Population. PLoS ONE. 2014 Jun 26;9(6):Article number e100060.<\/li>\n<li>Andri Hardiansyah, Li-Ying Huang, Ming-Chien Yang, Ting-Yu Liu, Sung-Chen Tsai, Chih-Yung Yang, Chih-Yu Kuo, Tzu-Yi Chan, Hui-Ming Zou, Wei-Nan Lian, <strong><u>Chi-Hung Lin<\/u><\/strong>. (2014) Magnetic liposomes for colorectal cancer cells therapy by high-frequency magnetic field treatment. Nanoscale Research Letters 2014 Sep, 9(1):497<\/li>\n<li>Hou ML, Chang LW, <strong><u>Lin CH<\/u><\/strong>, Lin LC, Tsai TH. (2014) Comparative pharmacokinetics of rhein in normal and loperamide-induced constipated rats and microarray analysis of drug-metabolizing genes. J Ethnopharmacol. 2014 Sep 11;155(2):1291-1299.<\/li>\n<li>Hsieh TH, Chien CL, Lee YH, Lin CI, Hsieh JY, Chao ME, Liu DJ, Chu SS, Chen W, Lin SC, Ho DM, Liu RS, <strong><u>Lin CH<\/u><\/strong>, Wong TT, Wang HW. (2014) Downregulation of SUN2, a novel tumor suppressor, mediates miR-221\/222-induced malignancy in central nervous system embryonal tumors. Carcinogenesis. 2014 Oct;35(10):2164-2174.<\/li>\n<li>Tseng JY, Yang CY, Liang SC, Liu RS, Jiang JK, <strong><u>Lin CH<\/u><\/strong>*. (2014) Dynamic changes in numbers and properties of circulating tumor cells and their potential applications. Cancers. 2014 Dec 16;6(4):2369-2386.<\/li>\n<li>Tsai PJ, Wang HS, Lin GJ, Chou SC, Chu TH, Chuan WT, Lu YJ, Weng ZC, Su CH, Hsieh PS, Sytwu HK, <strong><u>Lin CH<\/u><\/strong>, Chen TH, Shyu JF. (2015) Undifferentiated Wharton?s Jelly Mesenchymal Stem Cell Transplantation Induces Insulin-Producing Cell Differentiation and Suppression of T Cell-Mediated Autoimmunity in Non-Obese Diabetic Mice. Cell Transplant. 2015 Feb; 24(8):1555-1570<\/li>\n<li>Chen C, Chen CY, Yang CY, <strong><u>Lin CH<\/u><\/strong>, Cheng Y. (2015) Testosterone modulates preattentive sensory processing and involuntary attention switches to emotional voices. J Neurophysiol. 2015 Mar 15;113(6):1842-1849.<\/li>\n<li>Liang SC, Yang CY, Tseng JY, Wang HL, Tung CY, Liu HW, Chen CY, Yeh YC, Chou TY, Yang MH, Whang-Peng J, <strong><u>Lin CH<\/u><\/strong> *. (2015) ABCG2 Localizes to the Nucleus and Modulates CDH1 Expression in Lung Cancer Cells. Neoplasia. 2015 Mar;17(3):265-278.<\/li>\n<li>Tseng JY, Yang CY, Yang SH, Lin JK, <strong><u>Lin CH<\/u><\/strong>, Jiang JK. (2015) Circulating CD133+\/ESA+ cells in colorectal cancer patients. J Surg Res. 2015 Dec;199(2):362-370<\/li>\n<li>Yang CY, Tseng JY, Chen CF, Chou TY, Gao HW, Hua CL, <strong><u>Lin CH<\/u><\/strong>, Lin JK, Jiang JK. (2015) Genome-wide copy number changes and CD133 expression characterized distinct subset of colon polyps: differentiation between incidental polyps and cancer-associated polyps. Int J Colorectal Dis. 2015 Dec;30(12):1617-1626.<\/li>\n<li>Hou ML, <strong><u>Lin CH<\/u><\/strong>, Lin LC, Tsai TH. (2015) The drug-drug effects of rhein on the pharmacokinetics and pharmacodynamics of clozapine in rat brain extracellular fluid by in vivo microdialysis. J Pharmacol Exp Ther. 2015 Oct;355(1):125-134.<\/li>\n<li>Kao SY, Shyu JF, Wang HS, <strong><u>Lin CH<\/u><\/strong>, Su CH, Chen TH, Weng ZC, Tsai PJ. (2015) Comparisons of Differentiation Potential in Human Mesenchymal Stem Cells from Wharton&#8217;s Jelly, Bone Marrow, and Pancreatic Tissues. Stem Cells Int. 2015;2015:306158. Epub 2015 Jul 29.<\/li>\n<li>Chen YT, Shih CJ, Ou SM, Hung SC, <strong><u>Lin CH<\/u><\/strong>, Tarng DC; Taiwan Geriatric Kidney Disease (TGKD) Research Group. (2015) Periodontal Disease and Risks of Kidney Function Decline and Mortality in Older People: A Community-Based Cohort Study. Am J Kidney Dis. 2015 Aug;66(2):223-230.<\/li>\n<li>Tsai MT, Chen YT, <strong><u>Lin CH<\/u><\/strong>, Huang TP, Tarng DC. (2015) U-shaped curve mortality associated with platelet count among older people: a community-based cohort study. Blood. 2015 Sep 24;126(13):1633-1635.<\/li>\n<li>Yang CY, Liu HW, Tsai YC, Tseng JY, Liang SC, Chen CY, Lian WN, Wei MC, Lu M, Lu RH, <strong><u>Lin CH<\/u><\/strong>, Jiang JK. (2015) Interleukin-4 receptor-targeted liposomal doxorubicin as a model for enhancing cellular uptake and antitumor efficacy in murine colorectal cancer. Cancer Biol Ther. 2015 Oct;16(11):1641-1650.<\/li>\n<li>Chen HP, Jiang JK, Lai PY, Teo WH, Yang CY, Chou TY, <strong><u>Lin CH<\/u><\/strong>, Chan YJ. (2016) Serological and viraemic status of human cytomegalovirus infection in patients with colorectal cancer is not correlated with viral replication and transcription in tumours. J Gen Virol. 2016 Jan;97(1):152-159.<\/li>\n<li>Chien JY, Tsen SD, Chien CC, Liu HW, Tung CY and <strong><u>Lin CH<\/u><\/strong> *. (2016) \u03b1TAT1 downregulation induces mitotic catastrophe in HeLa and A549 cells. Cell Death Discovery 2016 Feb. Article number: 16006 (2016)<\/li>\n<li>Chien JY, <strong><u>Lin CH<\/u><\/strong> *. (2016) \u03b1TAT1: a potential therapeutic target in cancer? Cell Death Dis. 2016 Mar 31;7:e2172.<\/li>\n<li>Hou ML, Lu CM, <strong><u>Lin CH<\/u><\/strong>, Lin LC, Tsai TH. (2016) Pharmacokinetics of Maleic Acid as a Food Adulterant Determined by Microdialysis in Rat Blood and Kidney Cortex. Molecules. 2016 Mar 17;21(3):367.<\/li>\n<li>Liu CY, Han YY, Shih PH, Lian WN, Wang HH, <strong><u>Lin CH<\/u><\/strong>, Hsueh PR, Wang JK, Wang YL. (2016) Rapid bacterial antibiotic susceptibility test based on simple surface-enhanced Raman spectroscopic biomarkers. Sci Rep. 2016 Mar 21;6:23375.<\/li>\n<li>Hsueh TY, Ho JK, Lin LC, Chiu AW, <strong><u>Lin CH<\/u><\/strong>, Tsai TH. (2016) Herb-drug interaction of Epimedium extract on the pharmacokinetic of dapoxetine in rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Mar 1;1014:64-69.<\/li>\n<li>Lin TP, Chang YT, Lee SY, Campbell M, Wang TC, Shen SH, Chung HJ, Chang YH, Chiu AW, Pan CC, <strong><u>Lin CH<\/u><\/strong>, Chu CY, Kung HJ, Cheng CY, Chang PC. (2016) REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling. Oncotarget. 2016 Mar 28. 7(18):26137-26151<\/li>\n<li>Kuo CY, Liu TY, Chan TY, Tsai SC, Hardiansyah A, Huang LY, Yang MC, Lu RH, Jiang JK, Yang CY, <strong><u>Lin CH<\/u><\/strong>, Chiu WY. (2016) Magnetically triggered nanovehicles for controlled drug release as a colorectal cancer therapy. Colloids Surf B Biointerfaces. 2016 Apr 1;140:567-573.<\/li>\n<li>Shih CJ, Chen YT, Ou SM, <strong><u>Lin CH<\/u><\/strong>, Tarng DC; Taiwan Geriatric Kidney Disease (TGKD) Research Group. (2016) Observed Blood Pressure and Mortality Among People Aged 65 Years and Older: A Community-Based Cohort Study. J Am Med Dir Assoc. 2016 Jul 1;17(7):654-662.<\/li>\n<li>Chen HP, Jiang JK, Chen CY, Yang CY, Chen YC, <strong><u>Lin CH<\/u><\/strong>, Chou TY, Cho WL, Chan YJ. (2016) Identification of human cytomegalovirus in tumor tissues of colorectal cancer and its association with the outcome of non-elderly patients. J Gen Virol. 2016 Sep;97(9):2411-2420<\/li>\n<li>Chen TW, Liu HW, Liou YJ, Lee JH, <strong><u>Lin CH<\/u><\/strong> *. (2016) Over-expression of stomatin causes syncytium formation in nonfusogenic JEG-3 choriocarcinoma placental cells. Cell Biol Int. 2016 Aug;40(8):926-933.<\/li>\n<li>Lee JH, Hsieh CF, Liu HW, Chen CY, Wu SC, Chen TW, Hsu CS, Liao YH, Yang CY, Shyu JF, Fischer WB, <strong><u>Lin CH<\/u><\/strong>*. (2017) Lipid raft-associated stomatin enhances cell fusion. FASEB J. 2017 Jan;31(1):47-59.<\/li>\n<li>Hua K, Lin CH, Chen YL, <strong><u>Lin CH<\/u><\/strong>, Ping YH, Jou YS, Chen CF. (2017) Identification of Novel Cancer Fusion Genes Using Chromosome Breakpoints Screening. Oncology Reports. 2017 Apr;37(4):2101-2108.<\/li>\n<li>Liao KH, Chang SJ, Chang HC, Chien CL, Huang TS, Feng TC, Lin WW, Shih CC, Yang MH, Yang SH,<strong><u> Lin CH<\/u><\/strong>, Hwang WL, Lee OK. (2017) Endothelial angiogenesis is directed by RUNX1T1-regulated VEGFA, BMP4 and TGF-\u03b22 expression. PLoS One. 2017 Jun 22;12(6):e0179758.<\/li>\n<li>Chang TY, Tsai WC, Huang TS, Su SH, Chang CY, Ma HY, Wu CH, Yang CY, <strong><u>Lin CH<\/u><\/strong>, Huang PH, Cheng CC, Cheng SM, Wang HW. (2017) Dysregulation of endothelial colony-forming cell function by a negative feedback loop of circulating miR-146a and -146b in cardiovascular disease patients. PLoS One. 2017 Jul 20;12(7):e0181562.<\/li>\n<li>Liao CP, Lin TP, Li PC, Geary LA, Chen K, Vaikari VP, Wu JB, <strong><u>Lin CH<\/u><\/strong>, (2018) Gross ME, Shih JC. Loss of MAOA in epithelia inhibits adenocarcinoma development, cell proliferation and cancer stem cells in prostate. Oncogene. 2018 May 29. 37, 5175\u20135190.<\/li>\n<li>Lu IL, Chen C, Tung CY, Chen HH, Pan JP, Chang CH, Cheng JS, Chen YA, Wang CH, Huang CW, Kang YN, Chang HY, Li LL, Chang KP, Shih YH, <strong><u>Lin CH<\/u><\/strong>, Kwan SY, Tsai JW. (2018) Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice. Nat Commun. 2018 Jun 27;9(1):2498.<\/li>\n<li>Hua K, Chen YT, Chen CF, Tang YS, Huang TT, Lin YC, Yeh TS, Huang KH, Lee HC, Hsu MT, Chi CW, Wu CW, <strong><u>Lin CH<\/u><\/strong>, and Ping YH. (2018) miR-23a\/27a\/24-2 cluster promotes gastric cancer cell proliferation in a synergetic manner. Oncology Letters 2018 Aug;16(2):2319-2325<\/li>\n<li>Chang YT, Lin TP, Tang JT, Campbell M, Luo YL, Lu SY, Yang CP, Cheng TY, Chang CH, Liu TT, <strong><u>Lin CH<\/u><\/strong>, Kung HJ, Pan CC, Chang PC. (2018) HOTAIR is a REST-regulated lncRNA that promotes neuroendocrine differentiation in castration resistant prostate cancer. Cancer Lett. 2018 Oct 1;433:43-52.<\/li>\n<li>Wei-Ju Lin, Chien-Yi Tung, Muh-Yong Yen, Yu-Jiun Chan, <strong><u>Chi-Hung Lin<\/u><\/strong>* &amp; Po-Ren Hsueh. (2018) A Novel Target Pathogen Identification and Tracking System Using Capillary Electrophoresis-Random Amplified Polymorphic DNA. Scientific Reports 2018 Oct 18;8(1):15365<\/li>\n<li>Lin TP, Li J, Li Q, Li X, Liu C, Zeng N, Huang JM, Chu GC,<strong><u> Lin CH<\/u><\/strong>, Zhau HE, Chung LWK, Wu BJ, Shih JC. (2018) R1 Regulates Prostate Tumor Growth and Progression By Transcriptional Suppression of the E3 Ligase HUWE1 to Stabilize c-Myc. Mol Cancer Res. 2018 Dec;16(12):1940-1951<\/li>\n<li>Wei-Cheng Tseng, Yung-Tai Chen, Yao-Ping Lin, Shuo-Ming Ou, Chih-Yu Yang, <strong><u>Chi-Hung Lin<\/u><\/strong>, Der-Cherng Tarng , Taiwan Geriatric Kidney Disease (TGKD) Research Group. (2019) Hyperuricemia Predicts an Early Decline in Renal Function among Older People: A Community-Based Cohort Study. Sci Rep. 2019 Jan 30;9(1):980<\/li>\n<li>Hsueh-Yao Chu, Long-Sheng Lu, Wanying Cho, Shin-Yao Wu, Yu-Cheng Chang, Chien-Ping Lin, Chih-Yung Yang, <strong><u>Chi-Hung Lin<\/u><\/strong>, Jeng-Kai Jiang, Fan-Gang Tseng. (2019) Enumerating Circulating Tumor Cells with a Self-Assembled Cell Array (SACA) Chip: A Feasibility Study in Patients with Colorectal Cancer. Cancers (Basel). 2019 Jan 8;11(1):56<\/li>\n<li>Cheng WC, Liao TT, Lin CC, Yuan LE, Lan HY, Lin HH, Teng HW, Chang HC, <strong><u>Lin CH<\/u><\/strong>, Yang CY, Huang SC, Jiang JK, Yang SH, Yang MH, Hwang WL. (2019) RAB27B-activated secretion of stem-like tumor exosomes delivers the biomarker microRNA-146a-5p, which promotes tumorigenesis and associates with an immunosuppressive tumor microenvironment in colorectal cancer. Int J Cancer. 2019 Oct 15;145(8):2209-2224<\/li>\n<li>Huang CY, Lee WJ, Lin HP, Chen RC, <strong><u>Lin CH<\/u><\/strong>, Peng LN, Chen LK. (2019) Epidemiology of frailty and associated factors among older adults living in rural communities in Taiwan. Arch Gerontol Geriatr. 2019 Nov 18;87:103986.<\/li>\n<li>Wu CY, Lee MB,<strong><u> Lin CH<\/u><\/strong>, Kao SC, Tu CC, Chang CM. (2020) A longitudinal study on psychological reactions and resilience among young survivors of a burn disaster in Taiwan 2015-2018. J Adv Nurs. 2020 Feb;76(2):514-525.<\/li>\n<li>C-S Lin, W-J Lee, S-Y Lin, H-P Lin, R-C Chen, <strong><u>C-H Lin<\/u><\/strong>, L-K Chen. (2020) Predicting New-Onset Diabetes Mellitus by Component Combinations of Premorbid Metabolic Syndrome among Older Adults in Taiwan. J Nutr Health Aging, 2020 March; 24(6):650-658.<\/li>\n<li>Wei-Che Tsai, Wei-Hui Chiang, Chun-Hsien Wu, Yue-Cheng Li, Mel Campbell, Po-Hsun Huang, Ming-Wei Lin, <strong><u>Chi-Hung Lin<\/u><\/strong>, Shu-Meng Cheng, Pei-Ching Chang, Cheng-Chung Cheng. (2020) miR-548aq-3p is a novel target of Far infrared radiation which predicts coronary artery disease endothelial colony forming cell responsiveness. Sci Rep. 2020 Apr 22;10(1):6805<\/li>\n<li>Hsu Ma, Kwang-Yi Tung, Shu-Ling Tsai, David L. Neil, Yun-Yi Lin, Hung-Tsang Yen, Kao-Li Lin, Yi-Ting Cheng, Shu-Chen Kao, Mei-Na Lin, Niann-Tzyy Dai, Cherng-Kang Perng, Tyng-Guey Wang, Hao-Chih Tai, Li-Ru Chen, Yung-Chang Tuan, <strong><u>Chi-Hung Lin<\/u><\/strong>*. (2020) Assessment and determinants of global outcomes among 445 mass-casualty burn survivors: A 2-year retrospective cohort study in Taiwan. BURNS, 2020 Sep;46(6):1444-1457<\/li>\n<li>Jun-Yi Chien , Yong-Chun Gu, Hsin-Mei Tsai, Chun-Hao Liu, Chia-Yuan Yen, Yuh-Lin Wang, Juen-Kai Wang, <strong><u>Chi-Hung Lin<\/u><\/strong>*. (2020) Rapid identifification of nicotine in electronic cigarette liquids based on surface-enhanced Raman scattering. Journal of Food and Drug Ananlysis 2020 27 June; 28:302-308<\/li>\n<li>Wei-Ju Lee, Ching-Yi Liu, Li-Ning Peng, <strong><u>Chi-Hung Lin<\/u><\/strong>, Hui-Ping Lin, Liang-Kung Chen. (2020) PM 2.5 air pollution contributes to the burden of frailty. Sci Rep. 2020 Sep 2;10(1):14478.<\/li>\n<li>Wei-Chih Cheng, Lu-Hung Chen, Ci-Ren Jiang, Yu-Ming Deng, Da-Wei Wang, <strong><u>Chi-Hung Lin<\/u><\/strong>, Ruwen Jou, Juen-Kai Wang, Yuh-Lin Wang. (2021) Sensible Functional Linear Discriminant Analysis Effectively Discriminates Enhanced Raman Spectra of Mycobacterium Species. Anal Chem. 2021 Feb 9; 93(5):2785-2792.<\/li>\n<li>Chun-Hsien Wu, Chin Heng Gan, Lan-Hui Li, Jen-Che Chang, Shin-Tai Chen, Mridula P Menon, Shu-Meng Cheng, Shih-Ping Yang, Chen-Lung Ho, Oleg V Chernikov, <strong><u>Chi-Hung Lin<\/u><\/strong>, Yulin Lam, Kuo-Feng Hua. (2021) Corrigendum: A Synthetic Small Molecule F240B Decreases NLRP3 Inflammasome Activation by Autophagy Induction. Front Immunol. 2021 Dec 15; 12:738591.<\/li>\n<li>Lu-Yen Anny Chen, Chia-Yi Wu, Ming-Been Lee, <strong><u>Chi-Hung Lin<\/u><\/strong>, Shu-Chen Kao, Chung-Chieh Tu, Ran-Chou Chen. (2022) Predictors for psychological distress of young burn survivors across three years: A cohort study of a burn disaster in Taiwan. J Nurs Scholarsh. 2022 Jan;54(1):56-63.<\/li>\n<li>Shao-Chin Wu, Yuan-Ming Lo, Jui-Hao Lee, Chin-Yau Chen, Tung-Wei Chen, Hong-Wen Liu, Wei-Nan Lian, Kate Hua, Chen-Chung Liao, Wei-Ju Lin, Chih-Yung Yang, Chien-Yi Tung, <strong><u>Chi-Hung Lin<\/u><\/strong>*.(2022) Stomatin modulates adipogenesis through the ERK pathway and regulates fatty acid uptake and lipid droplet growth. Nat Commun. 2022 Jul 19;13(1):4174.<\/li>\n<li>Yun-Ti Chen, Yu-Hsiu Chang, Nikhil Pathak, Shey-Cherng Tzou, Yong-Chun Luo, Yen-Chao Hsu, Tian-Neng Li, Jung-Yu Lee, Yi-Cyun Chen, Yu-Wei Huang, Hsin-Ju Yang, Nung-Yu Hsu, Hui-Ping Tsai, Tein-Yao Chang, Shu-Chen Hsu, Ping-Cheng Liu, Yuan-Fan Chin, Wen-Chin Lin, Chuen-Mi Yang, Hsueh-Ling Wu, Chia-Ying Lee, Hui-Ling Hsu, Yi-Chun Liu, Jhih-Wei Chu, Lily Hui-Ching Wang , Jann-Yuan Wang , Chih-Heng Huang, <strong><u>Chi-Hung Lin<\/u><\/strong>, Po-Shiuan Hsieh, Yan-Hwa Wu Lee, Yi-Jen Hung, Jinn-Moon Yang. (2022) Methotrexate inhibition of SARS-CoV-2 entry, infection and inflammation revealed by bioinformatics approach and a hamster model. Front Immunol. 2022 Dec 21:13:1080897.<\/li>\n<li>Wei-Ju Lin, Wei-Ju Lee, Li-Ning Peng, Yi-Long Huang, Chien-Yi Tung, <strong><u>Chi-Hung Lin<\/u><\/strong>, Ting-Fen Tsai, Liang-Kung Chen. (2023) Anti-tumor necrosis factor-\u03b1 is potentially better than tumor necrosis factor-\u03b1 as the biomarker for sarcopenia: Results from the I-Lan longitudinal aging study. Exp Gerontol. 2023 Feb:172:112053.<\/li>\n<li>Chun-Chi Lin, Chih-Yung Yang, Tzu-Chao Hung, Chun-Hung Wang, Sheng-Wen Wei, Perry Schiro, Ju-Yu Tseng, <strong><u>Chi-Hung Lin<\/u><\/strong>, Jeng-Kai Jiang. (2023) MiSelect R System: the validation of a new detection system of CTCs and their correlation with prognosis in non-metastatic CRC patients. Sci Rep. 2023 Mar 23;13(1):4773.<\/li>\n<li>Chih-Yung Yang, Chun-Chi Lin, Sheng-Chieh Huang, Ruey-Hwa Lu, Liang-Chuan Lo, Ju-Yu Tseng, Chien-Yi Tung, <strong><u>Chi-Hung Lin<\/u><\/strong>, Jeng-Kai Jiang. (2023) Enhanced prognostic value of combined circulating tumor cells and serum carcinoembryonic antigen in patients with colorectal cancer. J Chin Med Assoc. 2023 May 1;86(5):465-471.<\/li>\n<li>Shao-Chin Wu, <strong><u>Chi-Hung Li<\/u><\/strong>n*. (2023) Direct Adeno-associated Viruses Injection of Murine Adipose Tissue. Bio Protoc. 2023 May 20;13(10):e4674.<\/li>\n<li>Chien JY, Gu YC, Liu CH, Tsai HM, Lee CN, Yang AC, Huang J, Wang YL, Wang JK, <strong><u>Lin CH<\/u><\/strong>*. (2023) Rapid detection of nicotine and benzoic acid in e-liquids with surface-enhanced Raman scattering and artificial intelligence-assisted spectrum interpretation. J Pharm Biomed Anal. 2023 Sep 5;233:115456.<\/li>\n<li>Li-Yu Fay, Jun-Yi Chien, Ching-Feng Weng, Huai-Sheng Kuo, Dann-Ying Liou, Wei-Hao Weng, <strong><u>Chi-Hung Lin<\/u><\/strong>, Ya-Tzu Chen, Wen-Hung Huang, Wen-Cheng Huang, May-Jywan Tsai, Henrich Cheng. (2023) Evaluating the toxic mechanism of 1,2-diacetylbenzene in neural cells\/tissues: The favorable impact of silibinin. Neurotoxicology 2023 Dec:99:313-321.<\/li>\n<li>Jiang JK*, <strong><u>Lin CH*<\/u><\/strong>, Chang TA, Lo LC, Lin CP, Lu RH, Yang CY. Decreased interleukin-17RA expression is associated with good prognosis in patients with colorectal cancer and inhibits tumor growth and vascularity in mice. Cancer Medicine. 2024, Mar; 13(5): e7059. doi: 10.1002\/cam4.7059(* first author)<\/li>\n<\/ol>\n<h2>\u8a08\u756b<\/h2>\n<p>\u8a08\u756b\u540d\u7a31\uff1a\u570b\u7acb\u967d\u660e\u4ea4\u901a\u5927\u5b78-\u79d1\u7814\u7522\u696d\u5316\u5e73\u53f0\u8a08\u756b(114-2622-8-A49-009-NSB)<\/p>\n<p>\u88dc\u52a9\u55ae\u4f4d\uff1a\u570b\u79d1\u6703<\/p>\n<p>\u57f7\u884c\u671f\u9650\uff1a2025\/04\/01~2026\/03\/31<\/p>\n<p>\u8a08\u756b\u5167\u64d4\u4efb\u5de5\u4f5c\uff1a\u4e3b\u6301\u4eba<\/p>\n<p>\u7d93\u8cbb\u7e3d\u984d\uff1a61,485,000<\/p>\n<p>\u8a08\u756b\u540d\u7a31\uff1a\u9081\u54112030\u5e74\u667a\u6167\u91ab\u7642\u5927\u5065\u5eb7\u8de8\u57df\u8a08\u756b(II)(2\/2) (113-2634-F-A49 -003 )<\/p>\n<p>\u88dc\u52a9\u55ae\u4f4d\uff1a\u570b\u79d1\u6703<\/p>\n<p>\u57f7\u884c\u671f\u9650\uff1a2024\/11\/01 ~ 2025\/10\/31<\/p>\n<p>\u8a08\u756b\u5167\u64d4\u4efb\u5de5\u4f5c\uff1a\u4e3b\u6301\u4eba<\/p>\n<p>\u7d93\u8cbb\u7e3d\u984d\uff1a41,000,000<\/p>\n<p>\u8a08\u756b\u540d\u7a31\uff1a\u81fa\u7063\u57fa\u56e0\u9ad4\u61c9\u7528\u7814\u767c\u3001\u6280\u8853\u53ca\u7522\u696d\u751f\u614b\u7cfb(3\/3) (114-2622-8-A49 -007 -TB)<\/p>\n<p>\u88dc\u52a9\u55ae\u4f4d\uff1a\u570b\u79d1\u6703<\/p>\n<p>\u57f7\u884c\u671f\u9650\uff1a2025\/04\/01~2026\/03\/31<\/p>\n<p>\u8a08\u756b\u5167\u64d4\u4efb\u5de5\u4f5c\uff1a\u4e3b\u6301\u4eba<\/p>\n<p>\u7d93\u8cbb\u7e3d\u984d\uff1a2,300,000<\/p>\n<\/div>\n<\/section>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<div id=\"tab_laboratory-overview\" class=\"panel entry-content\" role=\"tabpanel\" aria-labelledby=\"tab-laboratory-overview\">\n<h2>\u5be6\u9a57\u5ba4\u7db2\u5740<\/h2>\n<p><a href=\"https:\/\/sites.google.com\/view\/chl-lab\/\u9996\u9801?authuser=0\">https:\/\/sites.google.com\/view\/chl-lab\/\u9996\u9801?authuser=0<\/a><\/p>\n<h2>\u7814\u7a76\u65b9\u5411<\/h2>\n<p>\u6797\u5947\u5b8f\u8001\u5e2b\u4e3b\u6301\u7684\u7d30\u80de\u7d1a\u764c\u75c7\u751f\u7269\u5b78\u5be6\u9a57\u5ba4\u6574\u5408\u4e86\u57fa\u790e\u5206\u5b50\u751f\u7269\u3001\u81e8\u5e8a\u91ab\u5b78\u3001\u751f\u7269\u8cc7\u8a0a\u3001\u986f\u5fae\u93e1\u5b78\u7b49\u6280\u8853\u548c\u8cc7\u6e90\uff0c\u81f4\u529b\u65bc\u7814\u7a76\u5927\u8178\u76f4\u8178\u764c\u3001\u524d\u5217\u817a\u764c\u53ca\u8166\u764c\u7b49\u764c\u75c7\u767c\u5c55\u7684\u5206\u5b50\u6a5f\u5236\uff0c\u4ee5\u53ca\u764c\u75c7\u6cbb\u7642\u7b56\u7565\u4e4b\u7814\u7a76\u3002\u6211\u5011\u7684\u7814\u7a76\u6db5\u84cb\u4e86\u5c0b\u627e\u6f5b\u5728\u81f4\u764c\u57fa\u56e0\uff0c\u764c\u75c7\u7684\u4fe1\u865f\u50b3\u5c0e\u8def\u5f91\uff0c\u816b\u7624\u5fae\u74b0\u5883\u5f71\u97ff\u4ee5\u53ca\u764c\u75c7\u6297\u85e5\u6a5f\u5236\u7b49\u591a\u500b\u9762\u5411\u3002<\/p>\n<h2>\u5be6\u9a57\u5ba4\u6210\u54e1<\/h2>\n<p><a href=\"https:\/\/sites.google.com\/view\/chl-lab\/lab-member\">https:\/\/sites.google.com\/view\/chl-lab\/lab-member<\/a><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-632\" src=\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/image001-2.jpg\" alt=\"\" width=\"1318\" height=\"989\" srcset=\"https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/image001-2.jpg 1318w, https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/image001-2-300x225.jpg 300w, https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/image001-2-1024x768.jpg 1024w, https:\/\/imi.nycu.edu.tw\/wp-content\/uploads\/2025\/06\/image001-2-768x576.jpg 768w\" sizes=\"auto, (max-width: 1318px) 100vw, 1318px\" \/><\/p>\n<\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":1230,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[29],"tags":[],"class_list":["post-1228","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-affiliated-faculty"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - 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